1060735-41-2Relevant academic research and scientific papers
Block synthesis of tetra- and hexasaccharides (β-D-glycero-D-manno- hepp-(1→4)-[α-L-rhap-(1→3)-β-D-glycero-D-manno-hepp- (1→4)]n-α-L-rhap-OMe (n = 1 and 2)) corresponding to multiple repeat units of the glycan from the surface-layer glycoprotein from Bacillus thermoaerophilus
Crich, David,Li, Ming
experimental part, p. 7003 - 7010 (2009/05/07)
(Chemical Equation Presented) A fully stereocontrolled block synthesis of the title tetra- and hexasaccharides has been achieved taking advantage of the ability of the 4,6-O-benzylidene acetal to control the stereochemistry of the β-D-glycero-D-mannoheptopyranoside unit and of a 2,3-O-diphenylmethylene acetal to install the α-L-rhamnopyranosidic linkages. Comparison of the spectral data for the hexasaccharide with that of the natural isolate confirms the structure of this very unusual and structurally challenging glycan.
