1061262-00-7

Basic information

• Product Name: N^ω-benzyloxycarbonyl-N^ω'-(but-3-enyl)-N^α-tert-butyloxycarbonyl-L-arginine tert-butyl ester
• Synonyms: N^ω-benzyloxycarbonyl-N^ω'-(but-3-enyl)-N^α-tert-butyloxycarbonyl-L-arginine tert-butyl ester
• CAS NO: 1061262-00-7
• Molecular Weight: 518.654
• Mol File: 1061262-00-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N^ω-benzyloxycarbonyl-N^ω'-(but-3-enyl)-N^α-tert-butyloxycarbonyl-L-arginine tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N^ω-benzyloxycarbonyl-N^ω'-(but-3-enyl)-N^α-tert-butyloxycarbonyl-L-arginine tert-butyl ester(1061262-00-7)
• EPA Substance Registry System: N^ω-benzyloxycarbonyl-N^ω'-(but-3-enyl)-N^α-tert-butyloxycarbonyl-L-arginine tert-butyl ester(1061262-00-7)

Safety Data

• Hazardous Substances Data: 1061262-00-7(Hazardous Substances Data)

Upstream product

• 1061261-89-9 N^ω-benzyloxycarbonyl-N^α-tert-butyloxycarbonyl-L-thiocitrulline tert-butyl ester 
• 17875-18-2 but-3-en-1-amine hydrochloride 

Relevant articles and documents

Efficient synthesis of optically pure Nω-alkylated L-arginines

A number of Nω-substituted L-arginines have been described to date, particularly with regard to nitric oxide synthase (NOS) modulators. Elaborate multistep syntheses and low yields limit the scope of preparing these modified L-arginines. We describe a synthetic methodology that delivers N ω-alkylated L-arginine derivatives from protected L-ornithine in a three-step sequence with excellent overall yields (81-90%) and in high purity. Analysis of the synthesized amino acids on a Crownpak Cr(+) column revealed no significant racemization, that is, >99.9% ee for all final compounds. Georg Thieme Verlag Stuttgart.