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1061284-60-3

1061284-60-3

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1061284-60-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1061284-60-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,6,1,2,8 and 4 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1061284-60:
(9*1)+(8*0)+(7*6)+(6*1)+(5*2)+(4*8)+(3*4)+(2*6)+(1*0)=123
123 % 10 = 3
So 1061284-60-3 is a valid CAS Registry Number.

1061284-60-3Downstream Products

1061284-60-3Relevant articles and documents

Synthesis and evaluation of α,α′-disubstituted phenylacetate derivatives for T-type calcium channel blockers

Lee, Hyung Kook,Lee, Yun Suk,Roh, Eun Joo,Rhim, Hyewhon,Lee, Jae Yeol,Shin, Kye Jung

scheme or table, p. 4424 - 4427 (2009/04/06)

We have synthesized and evaluated α,α′-disubstituted phenylacetate derivatives that were designed as T-type calcium channel blockers. Among them, compound 10e (IC50 = 8.17 ± 0.48 nM) showed the most potent T-type calcium current blocking activity and higher potency than Mibefradil (IC50 = 1.34 ± 0.49 μM). The PK profile and subtype selectivity over L-type calcium channel were satisfied for further animal assay using disease model.

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