106134-85-4

Basic information

• Product Name: Methanone, [1-(3-chloropropyl)-4-piperidinyl]phenyl-
• CAS NO: 106134-85-4
• Molecular Formula: C15H20ClNO
• Molecular Weight: 265.783
• Mol File: 106134-85-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Methanone, [1-(3-chloropropyl)-4-piperidinyl]phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, [1-(3-chloropropyl)-4-piperidinyl]phenyl-(106134-85-4)
• EPA Substance Registry System: Methanone, [1-(3-chloropropyl)-4-piperidinyl]phenyl-(106134-85-4)

Safety Data

• Hazardous Substances Data: 106134-85-4(Hazardous Substances Data)

Upstream product

• 109-70-6 1.3-chlorobromopropane 
• 37586-22-4 4-benzoylpiperidine 
• 25519-80-6 4-(benzoyl)piperidine hydrochloride 

Downstream Products

• 1560968-09-3 4-(3-(4-(cyclobutyl(hydroxy)(phenyl)methyl)piperidin-1-yl)propoxy)benzonitrile 
• 1560968-13-9 4-(3-(4-(cyclohexyl(hydroxy)(phenyl)methyl)piperidin-1-yl)propoxy)benzonitrile 
• 1560967-93-2 4-(3-(4-(hydroxydiphenylmethyl)piperidin-1-yl)propoxy)benzonitrile 
• 1560968-04-8 4-(3-(4-(1-hydroxy-1-phenylpentyl)piperidin-1-yl)propoxy)benzonitrile 
• 1560968-05-9 4-(3-(4-(cyclopropyl(hydroxy)(phenyl)methyl)piperidin-1-yl)propoxy)benzonitrile 
• 1560968-07-1 4-(3-(4-(1-hydroxy-2-methyl-1-phenylpropyl)piperidin-1-yl)propoxy)benzonitrile 
• 1560968-12-8 4-(3-(4-(cyclopentyl(hydroxy)(phenyl)methyl)piperidin-1-yl)propoxy)benzonitrile 
• 1560968-27-5 4-(3-(4-(cyclopentyl(amino)(phenyl)methyl)piperidin-1-yl)propoxy)benzonitrile 
• 1560968-58-2 4-(3-(4-(azido(cyclopentyl)(phenyl)methyl)piperidin-1-yl)propoxy)benzonitrile 
• 149668-24-6 4,5-dihydro-1-methyl-5-[3-(4-benzoylpiperidin-1-yl)propyl][1,2,4]triazolo[4,3-a]quinoxaline 

Relevant articles and documents

MENIN-MLL INHIBITORS AND METHODS OF USE THEREOF

The present invention relates generally to compounds that inhibit the binding of menin and MLL or MLL fusion proteins and methods of use thereof. In particular embodiments, the present invention provides compositions comprising piperdine-containing compounds and methods of use thereof to inhibit the interaction of menin with MLL oncoproteins (e.g., MLL1, MLL2, MLL-fusion oncoproteins), for example, for the treatment of leukemia, solid cancers, diabetes, and other diseases dependent on activity of MLL1, MLL2, MLL fusion proteins, MLL-PTD and/or menin.

Tricyclic triazolo derivatives, processes for producing the same and the uses of the same

Novel tricyclic triazolo derivatives and pharmaceutically acceptable salts thereof, which are useful as anti-inflammation agents, anti-allergy agents or anti-PAF agents as well as processes for producing the same are disclosed. The triazolo derivatives of