106137-27-3

Basic information

• Product Name: exo-2,3-bis(hydroxymethyl)-7-oxabicyclo[2.2.1]hept-5-ene
• CAS NO: 106137-27-3
• Molecular Weight: 156.181
• Mol File: 106137-27-3.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: exo-2,3-bis(hydroxymethyl)-7-oxabicyclo[2.2.1]hept-5-ene(CAS DataBase Reference)
• NIST Chemistry Reference: exo-2,3-bis(hydroxymethyl)-7-oxabicyclo[2.2.1]hept-5-ene(106137-27-3)
• EPA Substance Registry System: exo-2,3-bis(hydroxymethyl)-7-oxabicyclo[2.2.1]hept-5-ene(106137-27-3)

Safety Data

• Hazardous Substances Data: 106137-27-3(Hazardous Substances Data)

Upstream product

• 6118-51-0 exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride 

Downstream Products

• 165727-57-1 cis-2,3-bis(4-methylbenzensulfonate)-7-oxa-bicyclo-[2.2.1]hept-5-ene-2,3-dimethanol 
• 132929-36-3 C₂₂H₂₀O₅ 
• 55423-53-5 (2-endo,3-exo)-7-oxabicyclo<2.2.1>heptane-2,3-dimethanol 
• 133147-37-2 (1S*,2S*,5S*,6S*)-2-n-butyl-5,6-dihydroxymethyl-cyclohex-3-en-1-ol 
• 133147-37-2 (1R*,2R*,5S*,6S*)-2-n-butyl-5,6-dihydroxymethyl-cyclohex-3-en-1-ol 
• 132929-46-5 5-endo-bromo-2-endo-3-exo-dibenzoyloxymethyl-6-exo-phenylselenyl-7-oxabicyclo<2.2.1>heptane 
• 139928-66-8 2,3-bis(benzoylthiomethyl)-7-oxabicyclo<2.2.1>hept-5-ene 
• 95-13-6 1-indene 
• 98652-59-6 (1S*,2S*,7R*,8R*,9R*)-2-methyl-8,9-bis(phenylsulfonyl)tricyclo<6.2.2.0^1.6>undeca-5,10-diene 
• 98652-59-6 (1S*,2S*,7R*,8S*,9S*)-2-methyl-8,9-bis(phenylsulfonyl)tricyclo<6.2.2.0^1.6>undeca-5,10-diene 
• 97909-51-8 (2-endo,3-exo)-7-oxabicyclo<2.2.1>heptane-2,3-dimethanol bis(4-methylbenzenesulfonate) 
• 98652-56-3 4-phenyl-5,6-dihydro-4H-indene 
• 108635-92-3 1-ethynyl-2-pentylbenzene 
• 53011-95-3 2,3-dimethylene-7-oxabicyclo<2.2.2>heptane 

Relevant articles and documents

Synthesis of thermally degradable epoxy adhesives

We have developed a new strategy for the synthesis of epoxide-containing polymers where the pendant reactive groups are connected to the main backbone via thermally labile oxonorbornene groups. The polymers were synthesized by radical 1,4-polymerization of the appropriate bicyclic diene monomer. The produced polymers can be crosslinked in the presence of a diamine and de-crosslinked by thermal treatment at 160 °C, which induces retro-Diels-Alder reaction and cleaves pendant groups from the polymer backbone, as confirmed by differential scanning calorimetry. The potential for the utilization of this polymer as a thermally removable adhesive was demonstrated by a simple adhesion test. This method provides access to thermally cleavable epoxy networks that can be quickly and irreversibly disintegrated into nonvolatile components upon heating to a specified temperature. Copyright

ANTICANCER AGENTS AND PROCESS OF MAKING THEREOF

Provided herein are compositions and processes of making of anticancer compounds useful for cancer treatments. These cyclohexenone compounds show an unexpected result against certain cancer cells compared to their known analogs.

Convenient synthesis of meso-cyclohexa-1,3-dienes by one-pot two-step deoxygenation of 7-oxabicyclo[2.2.1]hept-2-enes

Iron(III) hydroxide oxide was found to be an efficient catalyst for the ring-opening reaction of 5,6-cis-disubstituted 7-oxabicyclo[2.2.1]hept-2-enes with acetyl bromide in dichloromethane at room temperature to give cyclohexene derivatives with leaving groups (acetoxy or bromo groups) disposed on each allylic position. A successive one-pot treatment of the reaction mixture with zinc powder and tetrahydrofuran successfully induced reductive 1,4-elimination to afford synthetically useful 5,6-disubstituted mesocyclohexa-1,3-dienes in good-to-high yields. Georg Thieme Verlag Stuttgart.