106140-58-3

Upstream product

• 594-19-4 tert.-butyl lithium 
• 106140-56-1 methyl 5-(2,6,6-trimethylcyclohexen-1-yl)-4-penten-2-ynoate 
• 73395-75-2 (E)-2-(but-1-en-3-ynyl)-1,3,3-trimethylcyclohex-1-ene 

Downstream Products

• 106140-72-1 7-tert-butyl-3-methyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenal 
• 106140-66-3 19-nor-9-tert-butylretinonitrile 
• 106140-64-1 3-tert-butyl-5-(2,6,6-trimethylcyclohexen-1-yl)-2,4-pentadienal 
• 106140-71-0 9-cis,13-cis-19-nor-9-tert-butylretinal 
• 106140-61-8 3-tert-butyl-5-(2,6,6-trimethylcyclohexen-1-yl)-2,4-pentadien-1-ol 

Relevant academic research and scientific papers

Retinoids. 6. Preparation of alkyl- and trimethylsilyl-substituted retinoids via conjugate addition of cuprates to acetylenic esters

Five retinoids bearing the ethyl, tert-butyl, and trimethylsilyl groups in the 9-position of retinal and the ethyl and tert-butyl groups in the 13-position have been synthesized. The key step of the syntheses involves the conjugate addition of lithium die