106146-95-6

Basic information

• Product Name: (4R,5S)-2-Methoxy-5-(4-methoxy-phenyl)-2-methyl-[1,3]dioxolane-4-carboxylic acid methyl ester
• Synonyms: (4R,5S)-2-Methoxy-5-(4-methoxy-phenyl)-2-methyl-[1,3]dioxolane-4-carboxylic acid methyl ester
• CAS NO: 106146-95-6
• Molecular Weight: 282.293
• Mol File: 106146-95-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4R,5S)-2-Methoxy-5-(4-methoxy-phenyl)-2-methyl-[1,3]dioxolane-4-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5S)-2-Methoxy-5-(4-methoxy-phenyl)-2-methyl-[1,3]dioxolane-4-carboxylic acid methyl ester(106146-95-6)
• EPA Substance Registry System: (4R,5S)-2-Methoxy-5-(4-methoxy-phenyl)-2-methyl-[1,3]dioxolane-4-carboxylic acid methyl ester(106146-95-6)

Safety Data

• Hazardous Substances Data: 106146-95-6(Hazardous Substances Data)

Upstream product

• 3901-07-3 3-(4-methoxy-phenyl)acrylic acid methyl ester 
• 1445-45-0 Trimethyl orthoacetate 
• 122517-81-1 (2R,3S)-methyl 2,3-dihydroxy-3-(4-methoxyphenyl)propanoate 

Downstream Products

• 42399-48-4 (2S,3S)-threo-2-hydroxy-3-(2-aminophenylthio)-3-(4-methoxyphenyl)-propionic acid 

Relevant articles and documents

Asymmetric syntheses of (+)-diltiazem hydrochloride

Efficient enantioselective syntheses of the important cardiac drug (+)-cis-(2S,3S)-diltiazem from (E)-methyl 4-methoxyphenylpropenoate via either the (2R,3S)- or (2S,3R)-enantiomers of threo-methyl 3-(4-methoxyphenyl)-2,3- dihydroxypropanoate are described.