122517-81-1

Basic information

• Product Name: (2R,3S)-methyl 2,3-dihydroxy-3-(4-methoxyphenyl)propanoate
• Synonyms: (2R,3S)-methyl 2,3-dihydroxy-3-(4-methoxyphenyl)propanoate
• CAS NO: 122517-81-1
• Molecular Weight: 226.229
• Mol File: 122517-81-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: (2R,3S)-methyl 2,3-dihydroxy-3-(4-methoxyphenyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3S)-methyl 2,3-dihydroxy-3-(4-methoxyphenyl)propanoate(122517-81-1)
• EPA Substance Registry System: (2R,3S)-methyl 2,3-dihydroxy-3-(4-methoxyphenyl)propanoate(122517-81-1)

Safety Data

• Hazardous Substances Data: 122517-81-1(Hazardous Substances Data)

Upstream product

• 122431-48-5 methyl cis-5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan-4-carboxylate 
• 130718-76-2 cis-5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan-4-carbaldehyde 
• 127489-32-1 cis-5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan-4-carboxylic acid 
• 130718-70-6 erythro 3-(4-methoxyphenyl)-1,1-bis(p-tolylthio)propane-2,3-diol 
• 130796-22-4 3-hydroxy-3-(4-methoxyphenyl)-1,1-bis(p-tolylthio)propan-2-one 
• 108-05-4 vinyl acetate 
• 106146-94-5 methyl 2,3-dihydroxy-3-(4-methoxyphenyl)propanoate 
• 832-01-9 methyl p-methoxycinnamate 
• 153141-25-4 (1S)-N-(p-methoxycinamoyl)-2,10-camphorsultam 
• 34446-64-5 (E)-3-(4-methoxyphenyl)propenoyl chloride 
• 3901-07-3 3-(4-methoxy-phenyl)acrylic acid methyl ester 
• 186581-53-3 diazomethane 
• 212690-66-9 (2R,3S)-1-((1S,5R,7R)-10,10-Dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-2,3-dihydroxy-3-(4-methoxy-phenyl)-propan-1-one 
• 130852-60-7 3-(4-methoxyphenyl)-1,1-bis(p-tolylthio)-3-(trimethylsilyloxy)propan-2-one 

Downstream Products

• 68856-96-2 N-(tert-butoxycarbonyl)-O-methyl-D-tyrosine 
• 1415012-33-7 methyl 2-bromo-3-(4-methoxyphenyl)propanoate 
• 1415012-34-8 methyl 2-azido-3-(4-methoxyphenyl)propanoate 
• 94790-24-6 (2R)-tert-butoxycarbonylamino-3-(4-methoxyphenyl)propionic acid methyl ester 
• 42399-48-4 (2S,3S)-threo-2-hydroxy-3-(2-aminophenylthio)-3-(4-methoxyphenyl)-propionic acid 
• 123742-82-5 (2S,3R)-2-Acetoxy-3-chloro-3-(4-methoxy-phenyl)-propionic acid methyl ester 
• 205640-30-8 (2R,3S)-3-Azido-2-hydroxy-3-(4-methoxy-phenyl)-propionic acid methyl ester 
• 260354-46-9 (2S,3R)-2-{(S)-2-Benzylamino-2-[(4S,5S)-5-(4-methoxy-phenyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-acetylamino}-3-(tert-butyl-diphenyl-silanyloxy)-butyric acid methyl ester 
• 260354-51-6 (2S,3R)-2-{(S)-2-Amino-2-[(4S,5S)-5-(4-methoxy-phenyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-acetylamino}-3-(tert-butyl-diphenyl-silanyloxy)-butyric acid methyl ester 
• 260354-47-0 (3R,4S)-1-Benzyl-3-benzyloxy-4-[(4S,5S)-5-(4-methoxy-phenyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-azetidin-2-one 
• 260354-44-7 (3R,4S)-1-Benzyl-3-benzyloxy-4-[(1S,2S)-1,2-dihydroxy-2-(4-methoxy-phenyl)-ethyl]-azetidin-2-one 
• 260354-42-5 Acetic acid (2S,3R)-1-benzyl-2-[(4S,5S)-5-(4-methoxy-phenyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-4-oxo-azetidin-3-yl ester 
• 260354-45-8 (S)-3-Benzyl-4-[(4S,5S)-5-(4-methoxy-phenyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-oxazolidine-2,5-dione 
• 260354-43-6 (3R,4R)-1-Benzyl-3-hydroxy-4-[(4S,5S)-5-(4-methoxy-phenyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-azetidin-2-one 

Relevant articles and documents

Osmium tetroxide-(QN)2 PHAL in an ionic liquid: A highly efficient and recyclable catalyst system for asymmetric dihydroxylation of olefins

In Os-catalysed asymmetric dihydroxylation using NMO as a co-oxidant, the combination of an ionic liquid and the new bis-cinchona alkaloid 2 generated in situ from (QN)2PHAL during reaction provided a simple and practical approach to the recycling of both catalytic components (osmium tetroxide and chiral ligand).

Catalytic asymmetric dihydroxylation of olefins with recyclable osmate-exchanged chloroapatite catalyst

An osmate-exchanged chloroapatite (CAP-OsO4) catalyst was prepared by an ion-exchange technique. CAP-OsO4 efficiently catalyses asymmetric dihydroxylation of olefins including α,β-unsaturated esters and amides to afford the corresponding diols in high yields and enantioselectivities. The catalyst was reused for several cycles with consistent activity.

Asymmetric syn-Dihydroxylation of β-Substituted (2R)-N-(α,β-Enoyl)bornane-10,2-sultams

Variously β-substituted (2R)-N-[(E)-α,β-enoyl]bornane-10,2-sultams were oxidized with OsO4/4-methylmorpholine 4-oxide in a highly stereoselective manner. In all cases, the attack occurred on the C(α)-re face. The absolute configurations of all