106157-91-9

Basic information

• Product Name: Ethanone, 1-(2-amino-4-pyrimidinyl)-2-bromo- (9CI)
• Synonyms: Ethanone, 1-(2-amino-4-pyrimidinyl)-2-bromo- (9CI);1-(2-aminopyrimidin-4-yl)-2-bromoethanone;Ethanone, 1-(2-amino-4-pyrimidinyl)-2-bromo;1-(2-aMinopyriMidin-4-yl)-2-broMoethan-1-one
• CAS NO: 106157-91-9
• Molecular Formula: C₆H₆BrN₃O
• Molecular Weight: 216.03534
• Product Categories: ACETYLHALIDE;Pyrimidine
• Mol File: 106157-91-9.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethanone, 1-(2-amino-4-pyrimidinyl)-2-bromo- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(2-amino-4-pyrimidinyl)-2-bromo- (9CI)(106157-91-9)
• EPA Substance Registry System: Ethanone, 1-(2-amino-4-pyrimidinyl)-2-bromo- (9CI)(106157-91-9)

Safety Data

• Hazardous Substances Data: 106157-91-9(Hazardous Substances Data)

Usage

General Description

"Ethanone, 1-(2-amino-4-pyrimidinyl)-2-bromo- (9CI)" is a chemical compound that is specifically classified under organic compounds known as pyrimidinones. Pyrimidinones are compounds that contain a pyrimidine ring, which is a six-member aromatic heterocycle, conjugated with a ketone. This particular compound includes an additional bromine atom and amino group, that significantly influence its chemical properties. However, detailed information on its uses, toxicological and safety measures, physical and chemical properties is limited and not widely available in public domain. Further research and studies are needed to fully understand its potential applications and implications.

Upstream product

• 106157-82-8 4-Acetyl-2-aminopyrimidine 
• 106157-95-3 4-Acetyl-2-aminopyrimidine hydrobromide 

Downstream Products

• 951784-63-7 4-(2-amino-pyrimidin-4-yl)-2-benzoyl-4-oxo-butyric acid ethyl ester 
• 951784-65-9 5-(2-amino-pyrimidin-4-yl)-2-phenyl-furan-3-carboxylic acid ethyl ester 
• 951784-64-8 5-(2-amino-pyrimidin-4-yl)-2-phenyl-thiophene-3-carboxylicacid ethyl ester 
• 951784-67-1 5-(2-amino-pyrimidin-4-yl)-2-phenyl-furan-3-carboxylic acid 
• 951784-66-0 5-(2-amino-pyrimidin-4-yl)-2-phenyl-thiophene-3-carboxylic acid 
• 951782-48-2 5-(2-amino-pyrimidin-4-yl)-2-phenyl-1H-pyrrole-3-carboxylic acid amide hydrochloride 
• 951784-03-5 5-(2-amino-pyrimidin-4-yl)-2-phenyl-1H-pyrrole-3-carboxylic acid 
• 1403679-55-9 5-(2-aminopyrimidin-4-yl)-2-(5-chloro-2-methylphenyl)-N-(1-methylpiperidin-4-yl)-1H-pyrrole-3-carboxamide 
• 1403679-56-0 5-(2-aminopyrimidin-4-yl)-2-(5-chloro-2-methylphenyl)-N-phenyl-1H-pyrrole-3-carboxamide 
• 1403679-64-0 5-(2-aminopyrimidin-4-yl)-N-benzyl-2-(5-chloro-2-methylphenyl)-1H-pyrrole-3-carboxamide 
• 1403679-65-1 5-(2-aminopyrimidin-4-yl)-2-(5-chloro-2-methylphenyl)-N-(2-methylpropyl)-1H-pyrrole-3-carboxamide 
• 1403679-59-3 5-(2-aminopyrimidin-4-yl)-2-(5-chloro-2-methylphenyl)-N-(2-methoxyethyl)-1H-pyrrole-3-carboxamide 
• 1403679-60-6 5-(2-aminopyrimidin-4-yl)-2-(5-chloro-2-methylphenyl)-N-(2-fluoroethyl)-1H-pyrrole-3-carboxamide 
• 1403679-63-9 5-(2-aminopyrimidin-4-yl)-2-(5-chloro-2-methylphenyl)-N-[2-(methylamino)ethyl]-1H-pyrrole-3-carboxamide 

Relevant articles and documents

Heteroarylpyrrolopyridinones active as kinase inhibitors

Compounds represented by formula (I) wherein A, R1, R2, R3, R4, R5 and R6 are as defined in the specification or a pharmaceutically acceptable salt or solvate thereof, compositions thereof,

PYRROLOPYRROLONES ACTIVE AS KINASE INHIBITORS

Compounds represented by formula (I) wherein A, R1, R2, R3, and R4 are as defined in the specification, compositions thereof, and methods of use thereof.

2-Amino- and 2-Guanidino-4-thiazolylpyrimidines

The synthesis of the four possible 2-amino- and 2-guanidino-4-(2-amino- and 2-guanidinothiazolyl)pyrimidines is described and pKa values are calculated.Guanidinopyrimidines are more basic than guanidinothiazoles.However, the reverse is true of the corresponding amino heterocycles; the amino thiazole is more basic than the amino pyrimidine.