1061659-71-9

Basic information

• Product Name: (S)-2-(1-benzyl-2-piperidinyl)pyridine
• CAS NO: 1061659-71-9
• Molecular Weight: 252.359
• Mol File: 1061659-71-9.mol

Chemical Properties

• CAS DataBase Reference: (S)-2-(1-benzyl-2-piperidinyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(1-benzyl-2-piperidinyl)pyridine(1061659-71-9)
• EPA Substance Registry System: (S)-2-(1-benzyl-2-piperidinyl)pyridine(1061659-71-9)

Safety Data

• Hazardous Substances Data: 1061659-71-9(Hazardous Substances Data)

Upstream product

• 1061659-64-0 2-[1-(phenylmethyl)-2-piperidinyl]pyridine 

Downstream Products

• 46041-69-4 (S)-2-(2'-piperidinyl)pyridine 

Relevant articles and documents

Enantioselective Henry reaction catalyzed by CuII salt and bipiperidine

(Chemical Equation Presented) A complex derived from the enantiomeric bipiperidine and copper(II) acetate hydrate is an efficient catalyst for the enantioselective Henry reaction. The easy availability of both catalyst components, mild reaction conditions

Chiral ligand 2-(2′-piperidinyl)pyridine: synthesis, resolution and application in asymmetric diethylzinc addition to aldehydes

Chiral ligand 2-(2′-piperidinyl)pyridine 1 has been synthesized in good overall yield by sequential benzylation, hydrogenation and debenzylation of 2,2′-bipyridine. Its enantiomerically pure enantiomers have been obtained by resolution of 2-(1-benzyl-2-piperidinyl)pyridine 2 with d-tartaric acid (or l-tartaric acid) followed by debenzylation. The absolute configuration was determined by X-ray analysis of the (S)-2 d-tartrate. It was demonstrated that 1 can be used as an effective enantioselective catalyst in the addition of diethylzinc to aldehydes. Optically active secondary alcohols with up to 100% enantiomeric excess were obtained in high yields.