106247-35-2 Usage
Uses
2-Amino-4,4-dimethylpentanoic Acid is an unnatural amino acid used in vitro biological study of highly modified macrocyclic peptide analogs that act as tight binding inhibitors of thrombin.
Check Digit Verification of cas no
The CAS Registry Mumber 106247-35-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,2,4 and 7 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 106247-35:
(8*1)+(7*0)+(6*6)+(5*2)+(4*4)+(3*7)+(2*3)+(1*5)=102
102 % 10 = 2
So 106247-35-2 is a valid CAS Registry Number.
106247-35-2Relevant articles and documents
PEPTIDES CONTAINING A NEOPENTYLGLYCINE RESIDUE
Pospisek, Jan,Blaha, Karel
, p. 514 - 521 (2007/10/02)
Neopentylglycine (III, 2-amino-4,4-dimethylpentanoic acid) was synthesized in both enantiomeric forms.Using the conventional methods of peptide synthesis, L-prolyl-L-neopentylglycylglycine amide (VII), the diastereomeric cyclodipeptides cyclo(L-neopentylglycyl-L-prolyl) (IXa) and cyclo(D-neopentylglycyl-L-prolyl) (IXb) and also N-acetyl-L-neopentylglycine methylamide (X) were prepared as models for further studies on physical properties and conformation of peptides.