1062518-02-8

Basic information

• Product Name: (R)-pent-1-yne-1,3-diyldibenzene
• Synonyms: (R)-pent-1-yne-1,3-diyldibenzene
• CAS NO: 1062518-02-8
• Molecular Weight: 220.314
• Mol File: 1062518-02-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (R)-pent-1-yne-1,3-diyldibenzene(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-pent-1-yne-1,3-diyldibenzene(1062518-02-8)
• EPA Substance Registry System: (R)-pent-1-yne-1,3-diyldibenzene(1062518-02-8)

Safety Data

• Hazardous Substances Data: 1062518-02-8(Hazardous Substances Data)

Upstream product

• 313374-39-9 ethylphenylzinc 
• 27975-81-1 (+/-)-(3-bromopent-1-ynyl)benzene 
• 13146-23-1 copper(I) phenylacetylenide 
• 536-74-3 phenylacetylene 
• 90-27-7 2-Phenylbutyric acid 
• 2114-36-5 1-bromopropylbenzene 

Relevant articles and documents

Photoinduced Copper-Catalyzed Asymmetric Decarboxylative Alkynylation with Terminal Alkynes

We describe a photoinduced copper-catalyzed asymmetric radical decarboxylative alkynylation of bench-stable N-hydroxyphthalimide(NHP)-type esters of racemic alkyl carboxylic acids with terminal alkynes, which provides a flexible platform for the construction of chiral C(sp3)?C(sp) bonds. Critical to the success of this process are not only the use of the copper catalyst as a dual photo- and cross-coupling catalyst but also tuning of the NHP-type esters to inhibit the facile homodimerization of the alkyl radical and terminal alkyne, respectively. Owing to the use of stable and easily available NHP-type esters, the reaction features a broader substrate scope compared with reactions using the alkyl halide counterparts, covering (hetero)benzyl-, allyl-, and aminocarbonyl-substituted carboxylic acid derivatives, and (hetero)aryl and alkyl as well as silyl alkynes, thus providing a vital complementary approach to the previously reported method.

Method for synthesizing alkyne through catalytic asymmetric cross coupling (by machine translation)

The invention belongs to the field of, asymmetric synthesis, and discloses a method for catalyzing asymmetric cross- coupling to synthesize: an alkyne, and the L method comprises, the following steps, of A: preparing B a cuprous, salt and C a: ligand; preparing a catalyst; adding a base; reacting the compound with the compound with the compound; and reacting the compound with the compound. Of these, one of them, X is selected from the group consisting of, R halogens. 1 Optionally substituted heteroarylsulfonylcyanamide groups selected from the, group consisting, of optionally substituted, phenyl groups In-flight vehicle, R6 Trialkyl silyl groups or alkyl radicals, R2 Cycloalkyl radicals optionally substituted with an, optionally substituted alkyl, (CH radical2 )n R4 Multi,layer chain, n＝0-10,R saw blade4 A group selected, from, the group consisting of phenyl, alkenyl, aralkynyls, noonyloxy,and, noonylsulfonylsulfonylsulfonylsulfonylsulfonylsulfonylsulfonylsulfonylsulfonylsulphonylsulphonylsulphonylsulphonylsulphonylsulphonylsulphonylsulphonylsulphonylsulphonylphenyl disiloxy-radicals. R3 A ligand, selected from hydrogen or any of the functional groups, is selected from the group consisting of, hydrogen and any L other functional group. The method, R disclosed by the, A invention has the, advantages of good catalytic, R ’ effect, wide application range. and high catalytic efficiency, and the, method disclosed by the, invention has the. advantages of good catalytic effect, wide application range and high catalytic efficiency. (by machine translation)