106306-98-3

Upstream product

• 24376-18-9 3,4-dinitrobenzoyl chloride 
• 528-45-0 3,4-dinitrobenzoic acid 
• 106306-95-0 N-(3-dimethylaminopropyl)-3-nitro-4-acetylaminobenzamide 
• 556-08-1 p-(acetylamino)benzoic acid 
• 24170-23-8 3-nitro-4-acetylaminobenzoyl chloride 
• 1539-06-6 3-nitro-4-acetamidobenzoic acid 
• 106306-96-1 N-(3-dimethylaminopropyl)-3-nitro-4-aminobenzamide 

Downstream Products

• 106307-12-4 N-(3-dimethylaminopropyl)-2-(4-hydroxyphenyl)-5⁽⁶⁾-benzimidazolecarboxamide picrate 
• 106307-09-9 N-(3-dimethylaminopropyl)-2-(4-aminophenyl)-5⁽⁶⁾-benzimidazolecarboxamide trihydrochloride 
• 106307-05-5 N-(3-dimethylaminopropyl)-2-(4-acetylaminophenyl)-5⁽⁶⁾-benzimidazolecarboxamide 
• 136491-86-6 2'-(4-Methanesulfonylamino-phenyl)-1H,1'H-[2,5']bibenzoimidazolyl-5-carboxylic acid (3-dimethylamino-propyl)-amide; hydrochloride 
• 136491-84-4 2-<2-(4-nitrophenyl)-5(6)-benzimidazolyl>-N-(3-dimethylaminopropyl)-5(6)-benzimidazolecarboxamide trihydrochloride 
• 136491-85-5 2'-(4-Hydroxy-phenyl)-1H,1'H-[2,5']bibenzoimidazolyl-5-carboxylic acid (3-dimethylamino-propyl)-amide; hydrochloride 
• 121138-28-1 2'-Phenyl-1H,1'H-[2,5']bibenzoimidazolyl-5-carboxylic acid (3-dimethylamino-propyl)-amide 
• 106307-13-5 N-(3-dimethylaminopropyl)-2-(4-mesylamino)-5⁽⁶⁾-benzimidazolecarboxamide hydrochloride 
• 106307-04-4 N-(3-dimethylaminopropyl)-2-(4-nitrophenyl)-5⁽⁶⁾-benzimidazolecarboxamide 

Relevant academic research and scientific papers

BIS-BENZIMIDAZOLE COMPOUNDS AND METHODS OF USING SAME

Provided herein are compounds and methods for modulating abnormal repeat expansions of gene sequences. More particularly, provided are inhibitors of RNA and the uses of such inhibitors in regulating nucleotide repeat expansions, e.g., to treat Myotonic Dystrophy Type 1 (DM1 ), Myotonic Dystrophy Type 2 (DM2), Fuchs dystrophy, Huntington Disease, Amyotrophic Lateral Sclerosis, or Frontotemporal Dementia.

DERIVATIVES OF 5(6)-BENZIMIDAZOLECARBOXYLIC ACID

2-Aryl-5(6)-benzimidazolecarboxamides containing a 3-dimethylaminopropyl or 5-carboxypentyl group in the carboxamide fragment were synthesized by the condensation of the methoxyethylimidic esters of aromatic acids with o-diamines.