106352-41-4Relevant articles and documents
TRIFLUOROMETHYL GROUP INDUCED HIGHLY STEREOSELECTIVE SYNTHESIS OF α-HYDROXY CARBONYL COMPOUNDS
Morizawa, Yoshitomi,Yasuda, Arata,Uchida, Keiichi
, p. 1833 - 1836 (2007/10/02)
The reaction of enolate prepared from ethyl 3-methyl-4,4,4-trifluorobutyrate with MoO5-Py-HMPA complex provides ethyl (2S*,3S*)-2-hydroxy-3-methyl-4,4,4-trifluorobutyrate predominantly.In contrast, NaBH4 reduction of the corresponding 2-oxobutyrate affords (2R*,3S*)-hydroxyester preferentially.