106357-27-1

Basic information

• Product Name: (2S,3S,4R)-1-(tert-butyldiphenylsilyloxy)-2,4-dimethyl-hex-5-en-3-ol
• Synonyms: (2S,3S,4R)-1-(tert-butyldiphenylsilyloxy)-2,4-dimethyl-hex-5-en-3-ol
• CAS NO: 106357-27-1
• Molecular Weight: 382.618
• Mol File: 106357-27-1.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: (2S,3S,4R)-1-(tert-butyldiphenylsilyloxy)-2,4-dimethyl-hex-5-en-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S,4R)-1-(tert-butyldiphenylsilyloxy)-2,4-dimethyl-hex-5-en-3-ol(106357-27-1)
• EPA Substance Registry System: (2S,3S,4R)-1-(tert-butyldiphenylsilyloxy)-2,4-dimethyl-hex-5-en-3-ol(106357-27-1)

Safety Data

• Hazardous Substances Data: 106357-27-1(Hazardous Substances Data)

Upstream product

• 624-64-6 trans-2-Butene 
• 92817-88-4 (2S)-3-{[tert-butyl(diphenyl)silyl]oxy}-2-methylpropanal 
• 95514-04-8 (R)-3-(tert-butyldiphenylsilyloxy)-2-methylpropan-1-ol 
• 127793-69-5 (2S,4R)-5-{[tert-butyl(diphenyl)silyl]oxy}-2,4-dimethylpentanal 
• 99745-86-5 (S,S)-diisopropyl tartrate (E)-crotylboronate 
• 106357-20-4 (R,R)-diisopropyl tartrate (Z)-crotylboronate 
• 106357-33-9 (4S,5S)-2-[(2Z)-2-butenyl]-1,3,2-dioxaborolane-4,5-dicarboxylic acid bis(1-methylethyl) ester 
• 123284-89-9 (+/-)-2-methyl-3-[(tert-butyldiphenylsilyl)oxy]propanal 
• 35998-93-7 tri-n-butylcrotyltin 
• 99687-40-8 (R,R)-[(E)-2-butenyl]diisopropyl tartrate boronate 
• 122535-99-3 (R)-2-<<(Benzyloxy)methoxy>methyl>-1-<(tert-butyldiphenylsilyl)oxy>propane 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 95514-03-7 (S)-3-(tert-butyl-diphenyl-silanyloxy)-2-methyl-propionic acid methyl ester 
• 31197-41-8 crotyltributylstannane 

Downstream Products

• 908357-56-2 Methanesulfonic acid (1S,2R)-1-[(S)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-2-methyl-but-3-enyl ester 
• 713143-96-5 4-((3S,6R,8R,11R,13R)-3-Benzyl-4,6,8,11-tetramethyl-2,5-dioxo-1-oxa-4-aza-cyclotridec-13-yl)-butyraldehyde 
• 723296-19-3 (Z)-(3S,6R,8S,11S,13R)-3-Benzyl-13-(4-hydroxy-butyl)-4,6,8,11-tetramethyl-1-oxa-4-aza-cyclotridec-9-ene-2,5-dione 
• 723296-13-7 (3S,6R,8R,11R,13R)-3-benzyl-13-(4-hydroxy-butyl)-4,6,8,11-tetramethyl-1-oxa-4-azacyclotridecane-2,5-dione 
• 723296-12-6 (Z)-(3S,6R,8S,11S,13R)-3-Benzyl-13-[4-(tert-butyl-diphenyl-silanyloxy)-butyl]-4,6,8,11-tetramethyl-1-oxa-4-aza-cyclotridec-9-ene-2,5-dione 
• 723296-05-7 (S)-2-[((2R,4S)-2,4-Dimethyl-hex-5-enoyl)-methyl-amino]-3-phenyl-propionic acid (1R,3S)-1-[4-(tert-butyl-diphenyl-silanyloxy)-butyl]-3-methyl-pent-4-enyl ester 
• 330157-41-0 C₂₆H₃₉ClO₂Si₂ 
• 129170-53-2 (3S,4R,5R,6S,7S)-8-(tert-Butyl-diphenyl-silanyloxy)-3,5,7-trimethyl-6-triethylsilanyloxy-oct-1-en-4-ol 
• 129032-46-8 (3S,4R,5S,7R)-8-(tert-Butyl-diphenyl-silanyloxy)-3,5,7-trimethyl-oct-1-en-4-ol 
• 129100-71-6 (3R,4R,5S,7R)-8-(tert-Butyl-diphenyl-silanyloxy)-3,5,7-trimethyl-oct-1-en-4-ol 
• 129100-70-5 (3S,4S,5S,7R)-8-(tert-Butyl-diphenyl-silanyloxy)-3,5,7-trimethyl-oct-1-en-4-ol 
• 129100-69-2 (3R,4S,5S,7R)-8-(tert-Butyl-diphenyl-silanyloxy)-3,5,7-trimethyl-oct-1-en-4-ol 
• 127793-70-8 (4S,5S,7R)-8-(tert-Butyl-diphenyl-silanyloxy)-5,7-dimethyl-oct-1-en-4-ol 
• 127909-71-1 (4R,5S,7R)-8-(tert-Butyl-diphenyl-silanyloxy)-5,7-dimethyl-oct-1-en-4-ol 

Relevant articles and documents

Electrochemical and photochemical approaches for the synthesis of the C28–C38 fragment of okadaic acid

Okadaic acid, a potent and selective inhibitor of Protein Phosphatases 1 and 2A (PP1 and PP2A), is widely used as a probe for various biochemical processes. We describe herein two innovative methods for the synthesis of the terminal C28–C38 fragment of the natural polyether. Suárez photochemical oxidative cyclization and electrochemical oxidation of malonates to their ketals equivalents have been successfully applied for the assembly of the key spiroketal core.

Step-economic synthesis of (+)-crocacin C: A concise crotylboronation/[3,3] -sigmatropic rearrangement approach

The step-economic total synthesis of (+)-crocacin C has been achieved in 20% yield from commercially available starting materials. This approach requires the isolation of only 8 intermediates and can provide a reliable supply of (+)-crocacin C for the development of new antifungal and crop protection agents.

Diastereoselective synthesis of useful building blocks by crotylation of β-branched α-methylaldehydes with potassium crotyltrifluoroborates

(Chemical Equation Presented) The diastereoselective construction of stereotriads having consecutive methyl, hydroxy, and methyl substituents was realized by the substrate-controlled crotylation of β-branched α-methylaldehydes with potassium crotyltrifluoroborates. Especially, crotylation of 2-(1,3-dithian-2-yl)propanal with potassium (E)- crotyltrifluoroborate afforded, in good yield and with excellent diastereoselectivity, a useful building block that has different and potential functional groups on both ends.