Welcome to LookChem.com Sign In|Join Free

CAS

  • or
Propanoic acid, 3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2-methyl-, methyl ester, (2S)- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

95514-03-7 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 95514-03-7 Structure
  • Basic information

    1. Product Name: Propanoic acid, 3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2-methyl-, methyl ester, (2S)-
    2. Synonyms:
    3. CAS NO:95514-03-7
    4. Molecular Formula: C21H28O3Si
    5. Molecular Weight: 356.537
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 95514-03-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Propanoic acid, 3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2-methyl-, methyl ester, (2S)-(CAS DataBase Reference)
    10. NIST Chemistry Reference: Propanoic acid, 3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2-methyl-, methyl ester, (2S)-(95514-03-7)
    11. EPA Substance Registry System: Propanoic acid, 3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2-methyl-, methyl ester, (2S)-(95514-03-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 95514-03-7(Hazardous Substances Data)

95514-03-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 95514-03-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,5,5,1 and 4 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 95514-03:
(7*9)+(6*5)+(5*5)+(4*1)+(3*4)+(2*0)+(1*3)=137
137 % 10 = 7
So 95514-03-7 is a valid CAS Registry Number.

95514-03-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (R)-methyl 3-(tert-butyl(diphenyl)silyloxy)-2-methylpropanoate

1.2 Other means of identification

Product number -
Other names (2R)-3-[(tert-butyldiphenylsilyl)oxy]-2-methyl-propionic methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:95514-03-7 SDS

95514-03-7Relevant articles and documents

Syntheses of Gymnothespirolignans B and C and Non-natural Isomer 9-Epi-gymnothespirolignan B

Ali, Ghada,Cuny, Gregory D.

supporting information, p. 10517 - 10525 (2021/07/31)

Syntheses of polycyclic spiro lignans gymnothespirolignans B and C as well as the unnatural isomer 9-epi-gymnothespirolignan B were accomplished using (R)-Roche ester and an appropriately substituted fluorenone. Key features of the convergent syntheses include coupling of the fluorenone and an iodo-alkene intermediate derived from (R)-Roche ester in the presence of the Lewis acid TiCl(OiPr)3, C9-O bond formation via an SN2 reaction with retention of stereochemistry, and diastereoselective hydrogenations of a common alkene intermediate guided by accessibility or positioning by the C8-methoxy.

Total Synthesis of the Alleged Structure of Crenarchaeol Enables Structure Revision**

Cunha, Ana V.,Havenith, Remco W. A.,Holzheimer, Mira,Minnaard, Adriaan J.,Schouten, Stefan,Sinninghe Damsté, Jaap S.

supporting information, p. 17504 - 17513 (2021/07/06)

Crenarchaeol is a glycerol dialkyl glycerol tetraether lipid produced exclusively in Archaea of the phylum Thaumarchaeota. This membrane-spanning lipid is undoubtedly the structurally most sophisticated of all known archaeal lipids and an iconic molecule in organic geochemistry. The 66-membered macrocycle possesses a unique chemical structure featuring 22 mostly remote stereocenters, and a cyclohexane ring connected by a single bond to a cyclopentane ring. Herein we report the first total synthesis of the proposed structure of crenarchaeol. Comparison with natural crenarchaeol allowed us to propose a revised structure of crenarchaeol, wherein one of the 22 stereocenters is inverted.

The discovery and evaluation of 3-amino-2(1H)-pyrazinones as a novel series of selective p38α MAP kinase inhibitors

Evans, Richard,Raubo, Piotr,Willis, Paul

supporting information, (2020/07/21)

The discovery and optimisation of a novel series of potent and selective p38α inhibitors is described. Evaluating the structure-activity relationship of an aminoalkyl substituent at the 3 position of the 2(1H)-pyrazinone core, p38α potency was increased 20000-fold. The most advanced compound (25) demonstrated excellent in vivo properties suitable for an inhaled route of administration.

Ring-closing metathesis approaches towards the total synthesis of rhizoxins

Altmann, Karl-Heinz,Liniger, Marc,Neuhaus, Christian M.

supporting information, (2020/10/18)

Efforts are described towards the total synthesis of the bacterial macrolide rhizoxin F, which is a potent tubulin assembly and cancer cell growth inhibitor. A significant amount of work was expanded on the construction of the rhizoxin core macrocycle by ring-closing olefin metathesis (RCM) between C(9) and C(10), either directly or by using relay substrates, but in no case was ringclosure achieved. Macrocycle formation was possible by ring-closing alkyne metathesis (RCAM) at the C(9)/C(10) site. The requisite diyne was obtained from advanced intermediates that had been prepared as part of the synthesis of the RCM substrates. While the direct conversion of the triple bond formed in the ring-closing step into the C(9)-C(10) E double bond of the rhizoxin macrocycle proved to be elusive, the corresponding Z isomer was accessible with high selectivity by reductive decomplexation of the biscobalt hexacarbonyl complex of the triple bond with ethylpiperidinium hypophosphite. Radical-induced double bond isomerization, full elaboration of the C(15) side chain, and directed epoxidation of the C(11)-C(12) double bond completed the total synthesis of rhizoxin F.

Stereoselective Synthesis of the C1-C22 Carbon Framework of (-)-Amphidinolide K

Chandankar, Somnath S.,Raghavan, Sadagopan

, p. 9584 - 9602 (2019/09/06)

Two stereoselective routes to the C7-C22 subunit of amphidinolide K are disclosed. Jacobsen's hydrolytic kinetic resolution and Sharpless' asymmetric dihydroxylation reactions have been employed for the construction of the tetrahydrofuran ring. The C10-C1

A natural ɑ - glucosidase inhibitor Penasulfate A synthetic method (by machine translation)

-

Paragraph 0029; 0050; 0051, (2019/02/04)

The invention provides a natural ɑ - glucosidase inhibitor Penasulfate A synthetic method, including by the 1, 12 - dodecanediol via 5 step synthesis 12 - thirteen carbon olefine acid, L - arabinose via the 3 step synthesis (2 S, 3 R) - 2, 3 - oxygen - isopropyl - 4 - pentene - 1, 2, 3 - triol, (S)- Roche ester via the 8 step synthesis of chiral methyl undecenyl fundamental frequency that mellow boron ester, 12 - thirteen alkenylene acid and (2 S, 3 R) - 2, 3 - oxygen - isopropyl - 4 - pentene - 1, 2, 3 - triol in GrubbsII catalyst under the action of the olefin metathesis reaction, and then with the (R)- piperidine - 2 - carboxylic acid methyl ester reaction to prepare amide, re-oxidation results in the aldehyde, Takai alkene alkylation by thirteen alkenylene iodide, with the insecticidal compositions of the fundamental frequency that chiral methyl mellow boron ester in Pd (PPh3 )4 Catalytic, ethyl alcohol thallium as alkali under the condition of the key Suzuki coupling, hydrogenation reduction, [...], sulfuric acid ester, shall Penasulfate A. The present invention provides natural product Penasulfate A throughout the synthetic route for the first time, the olefin metathesis reactions and Suzuki coupling as a key reaction, the line is comparatively simple high efficiency, a high degree of convergence, the operation is easy to grasp. (by machine translation)

Total Synthesis of the Proposed Structure of Penasulfate A: L -Arabinose as a Source of Chirality

Gao, Yangguang,Cao, Zhou,Zhang, Qiang,Guo, Rui,Ding, Fei,You, Qingliang,Bi, Jingjing,Zhang, Yongmin

, p. 1908 - 1916 (2019/08/20)

The total synthesis of putative penasulfate A was effectively achieved by a convergent strategy with a longest linear sequence of 14 steps and overall yield of 8.6%. The highlights of our strategy involved an E-selective olefin cross-metathesis, Suzuki cross-coupling, and a copper(I)-catalyzed coupling reaction.

Polyoxygenated Tertiary Alcohols: A Kiyooka Approach

Lücke, Daniel,Kalesse, Markus

supporting information, p. 10080 - 10083 (2019/07/18)

A Kiyooka aldol approach for the stereoselective synthesis of tertiary alcohols is presented. This approach allows for the incorporation of different substituents at all three remaining positions at the chiral center bearing the tertiary alcohol. To demon

(R)-N-(1-Methyl-2-hydroxyethyl)-13-(S)-methyl-arachidonamide (AMG315): A Novel Chiral Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes

Liu, Yingpeng,Ji, Lipin,Eno, Marsha,Kudalkar, Shalley,Li, Ai-Ling,Schimpgen, Marion,Benchama, Othman,Morales, Paula,Xu, Shu,Hurst, Dow,Wu, Simiao,Mohammad, Khadijah A.,Wood, Jodianne T.,Zvonok, Nikolai,Papahatjis, Demetris P.,Zhou, Han,Honrao, Chandrashekhar,MacKie, Ken,Reggio, Patricia,Hohmann, Andrea G.,Marnett, Lawrence J.,Makriyannis, Alexandros,Nikas, Spyros P.

supporting information, p. 8639 - 8657 (2018/10/02)

The synthesis of potent metabolically stable endocannabinoids is challenging. Here we report a chiral arachidonoyl ethanolamide (AEA) analogue, namely, (13S,1′R)-dimethylanandamide (AMG315, 3a), a high affinity ligand for the CB1 receptor (Ki o

Stereocontrolled Synthesis of Polypropionate Fragments based on a Building Block Assembly Strategy using Lithiation-Borylation Methodologies

Millán, Alba,Grigol Martinez, Pablo D.,Aggarwal, Varinder K.

supporting information, p. 730 - 735 (2018/01/26)

Polypropionates are important structural motifs in nature and are commonly made by iterative aldol or crotylation methodologies. Herein, an alternative strategy is presented in which stereochemically predefined building blocks, bearing appropriate functio

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 95514-03-7