1063635-48-2

Upstream product

• 79324-79-1 1-(3,5-dibromo-4-methoxyphenyl)ethanone 
• 100-10-7 4-dimethylamino-benzaldehyde 

Downstream Products

• 1063635-22-2 3-(3,5-dibromo-4-methoxyphenyl)-5-(4-N,N-dimethylphenyl)-isoxazole 
• 1063635-05-1 1-acetyl-3-(3,5-dibromo-4-methoxyphenyl)-5-(4-N,N-dimethylaminophenyl)-4,5-dihydro-1H-pyrazole 
• 1219102-13-2 6-carbethoxy-5-(4-N,N-dimethylaminophenyl)-3-(3,5-dibromo-4-methoxyphenyl)-2-cyclohexenone 
• 1204389-38-7 2-amino-3-cyano-4-(4-(N,N-dimethylamino)phenyl)-6-(3,5-dibromo-4-methoxyphenyl)-4H-pyran 
• 1204389-29-6 2-amino-3-cyano-4-(4-(N,N-dimethylamino)phenyl)-6-(3,5-dibromo-4-methoxyphenyl)-pyridine 

Relevant academic research and scientific papers

Synthesis and antimicrobial activity of some new cyanopyridine and cyanopyrans towards mycobacterium tuberculosis and other microorganisms

2-Amino-3-cyano-6-(3,5-dibromo-4-methoxyphenyl)-4-aryl-pyridines 2a-i are synthesized by the reaction of compounds (2E)-3-(3,5-dibrorno-4-rnethoxyphenyl)- l-arylprop-2-en-l-one la-i with malononitrile in the presence of ammonium acetate. Condensation of c

Synthesis, antimicrobial and antitubercular activity of some cyclohexenone and indazole derivatives

The scries of compounds 6-carbethoxy-5-aryl-3-(3,5-dibromo-4-methoxy phenyl)-2-cyclohexenones 2a-j are obtained from the (2E)-1-(3,5-dibromo-4- methoxyphenyl)-3-aryl-prop-2-en-1-ones 1a-j by Michael addition of ethyl aeetoaeetatc. followed by internal Claisen condensation. Reaction of 2a-j with hydrazine hydrate afforded the corresponding 6-(3,5-dibromo-4-methoxyphcnyl)-4- aryl-2,3a,4,5-tetrahydro-3H-indazol-3-ones 3a-j. The constitution of all the synthesized compounds have been established by elemental analyses, IR, 1H NMR and mass spectral data. All the compounds have been screened for their antimicrobial activities and compounds 2a-j have been tested for antitubercular activity.

Synthesis, antitubercular and antimicrobial activities of some new pyrazoline and isoxazole derivatives

Cyclocondensation of hydrazine hydrate with (2E)-1-(3,5-dibromo-4- methoxyphenyl)-3-aryl-prop-2-en-1-ones (1a-j) in glacial acetic acid afford corresponding 1-acetyl-3-(3,5-dibromo-4-methoxyphenyl)-5-aryl-4,5-dihydro-1H- pyrazoles (2a-j). While the compounds 1a-j on reaction with hydroxylamine hydrochloride in presence of acetic acid and sodium acetate to give 3-(3,5-dibromo-4-methoxyphenyl)-5-aryl-isoxazoles (3a-j). All the compounds were tested against different microbes for their antimicrobial activity and compounds 2a-j were tested for antitubercular activity.