1063724-92-4

Basic information

• Product Name: 4-{[(4-(trifluoromethyl)-1,3-thiazol-2-yl)amino]sulfonyl}-N-[4-(trifluoromethyl)benzyl]benzamide
• Synonyms: 4-{[(4-(trifluoromethyl)-1,3-thiazol-2-yl)amino]sulfonyl}-N-[4-(trifluoromethyl)benzyl]benzamide
• CAS NO: 1063724-92-4
• Molecular Weight: 509.453
• Mol File: 1063724-92-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-{[(4-(trifluoromethyl)-1,3-thiazol-2-yl)amino]sulfonyl}-N-[4-(trifluoromethyl)benzyl]benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{[(4-(trifluoromethyl)-1,3-thiazol-2-yl)amino]sulfonyl}-N-[4-(trifluoromethyl)benzyl]benzamide(1063724-92-4)
• EPA Substance Registry System: 4-{[(4-(trifluoromethyl)-1,3-thiazol-2-yl)amino]sulfonyl}-N-[4-(trifluoromethyl)benzyl]benzamide(1063724-92-4)

Safety Data

• Hazardous Substances Data: 1063724-92-4(Hazardous Substances Data)

Upstream product

• 349-49-5 4-(trifluoromethyl)-1,3-thiazol-2-amine 
• 1063732-96-6 4-({[4-(trifluoromethyl)benzyl]amino}carbonyl)benzenesulfonyl chloride 

Relevant articles and documents

INHIBITORS OF ION CHANNELS

Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-gated sodium channels. More particularly, the invention provides substituted aryl sulfonamides, compositions comprising these compounds, as well as methods of using these compounds or compositions in the treatment of central or peripheral nervous system disorders, particularly pain and chronic pain by blocking sodium channels associated with the onset or recurrence of the indicated conditions. The compounds, compositions and methods of the present invention are of particular use for treating neuropathic or inflammatory pain by the inhibition of ion flux through a voltage-gated sodium channel.