349-49-5Relevant articles and documents
A novel access to 4-trifluoromethyl-1,3-thiazole derivatives via an intermediate thiocarbonyl ylide
Obijalska, Emilia,B?aszczyk, Magdalena,Kowalski, Marcin K.,Mlostoń, Grzegorz,Heimgartner, Heinz
, p. 35 - 40 (2019/02/25)
A Lewis acid catalyzed reaction of trifluoroacetyldiazomethane (CF3COCHN2) with thiourea occurs in boiling THF solution in the presence of BF3·OEt2 yielding 2-amino-4-trifluoromethyl-1,3-thiazole in a fair yield
Thiazolides as novel antiviral agents. 2. Inhibition of hepatitis c virus replication
Stachulski, Andrew V.,Pidathala, Chandrakala,Row, Eleanor C.,Sharma, Raman,Berry, Neil G.,Lawrenson, Alexandre S.,Moores, Shelley L.,Iqbal, Mazhar,Bentley, Joanne,Allman, Sarah A.,Edwards, Geoffrey,Helm, Alison,Hellier, Jennifer,Korba, Brent E.,Semple, J. Edward,Rossignol, Jean-Francois
supporting information; experimental part, p. 8670 - 8680 (2012/02/16)
We report the activities of a number of thiazolides [2-hydroxyaroyl-N- (thiazol-2-yl)amides] against hepatitis C virus (HCV) genotypes IA and IB, using replicon assays. The structure-activity relationships (SARs) of thiazolides against HCV are less predic
CARBACEPHEM β-LACTAM ANTIBIOTICS
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Page/Page column 92, (2010/04/06)
Carbacephem -lactam antibiotics having structure (I) are disclosed, including stereoisomers, pharmaceutically acceptable salts, esters and prodrugs thereof, wherein Ar1, Ar2, R1 and R2 are as defined herein. The compounds are useful for the treatment of bacterial infections, in particular those caused by methicillin-resistant Staphylococcus spp.