1064137-50-3

Basic information

• Product Name: 2,5-Dichloroquinoline-3-carbaldehyde
• Synonyms: 2,5-Dichloroquinoline-3-carbaldehyde;2,5-Dichloroquinoline-3-carboxaldehyde
• CAS NO: 1064137-50-3
• Molecular Formula: C₁₀H₅Cl₂NO
• Molecular Weight: 226.0588
• Mol File: 1064137-50-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,5-Dichloroquinoline-3-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Dichloroquinoline-3-carbaldehyde(1064137-50-3)
• EPA Substance Registry System: 2,5-Dichloroquinoline-3-carbaldehyde(1064137-50-3)

Safety Data

• Hazardous Substances Data: 1064137-50-3(Hazardous Substances Data)

Usage

General Description

2,5-Dichloroquinoline-3-carbaldehyde is a chemical compound with the molecular formula C11H6Cl2NO. It is a yellow to orange crystalline solid with a strong odor, and is commonly used as a building block in the synthesis of pharmaceuticals and other organic compounds. 2,5-Dichloroquinoline-3-carbaldehyde is also used in research and development processes in the pharmaceutical and chemical industries. 2,5-Dichloroquinoline-3-carbaldehyde has a variety of applications in the production of agrochemicals, dyes, and other specialty chemicals, making it a versatile and important chemical in the field of organic chemistry.

Upstream product

• 59412-12-3 2,5-dichloroquinoline 
• 68-12-2 N,N-dimethyl-formamide 
• 889939-13-3 ethyl 5-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate 
• 39885-08-0 (2-amino-6-chlorophenyl)methanol 
• 2148-56-3 2-chloro-6-aminobenzoic acid 
• 35490-90-5 2-amino-6-chlorobenzaldehyde 
• 109-94-4 formic acid ethyl ester 

Downstream Products

• 1065482-46-3 5-chloro-2-(3-fluorophenyl)quinoline-3-carbaldehyde 
• 1064136-44-2 1-((5-chloro-2-(2-(trifluoromethyl)phenyl)quinolin-3-yl)-methyl)-3-methyl-1H-pyrazolo [3,4-d]pyrimidin-4-amine 
• 1064137-00-3 (5-chloro-2-(2-(trifluoromethyl)-phenyl)quinolin-3-yl)methanol 
• 1065479-84-6 N-((S)-1-(5-chloro-2-(3-fluorophenyl)quinolin-3-yl)ethyl)-9H-purin-6-amine 
• 1065480-13-8 N-((R)-1-(5-chloro-2-(3-fluoro-phenyl)quinolin-3-yl)ethyl)-9H-purin-6-amine 
• 1065480-15-0 N-(1-(5-chloro-2-(3-fluorophenyl)quinolin-3-yl)ethyl)-9H-purin-6-amine 
• 1065482-48-5 2-(1-(5-chloro-2-(3-fluorophenyl)quinolin-3-yl)ethyl)isoindoline-1,3-dione 
• 1065482-47-4 1-(5-chloro-2-(3-fluorophenyl)quinolin-3-yl)ethanol 
• 1065482-49-6 1-(5-chloro-2-(3-fluorophenyl)quinolin-3-yl)ethanamine 
• 1064136-95-3 5-chloro-2-(2-(trifluoromethyl)phenyl)quinoline-3-carbaldehyde 

Relevant articles and documents

IMIDAZOPIPERAZINONE INHIBITORS OF TRANSCRIPTION ACTIVATING PROTEINS

The present disclosure relates to heterocyclic compounds and methods which may be useful as inhibitors of transcription activating proteins such as CBP and P300 for the treatment or prevention of diseases such as proliferative diseases, inflammatory disorders, autoimmune diseases, and fibrotic diseases.

HETEROCYCLIC COMPOUNDS AND THEIR USES

Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity. The present invention also enables methods for treating cancers that are mediated, dependent on, or associated with p110 activity, including but not restricted to leukemias, such as acute myeloid leukaemia (AML), myelo-dysplastic syndrome (MDS), myelo-proliferative diseases (MPD), chronic myeloid leukemia (CML), T-cell acute lymphoblastic leukaemia (T-ALL), B-cell acute lymphoblastic leukaemia (B-ALL), non Hodgkins lymphoma (NHL), B-cell lymphoma and solid tumors, such as breast cancer.