1064196-82-2Relevant academic research and scientific papers
Intramolecular Kulinkovich-de Meijere reactions of various disubstituted alkenes bearing amide groups
Madelaine, Claire,Ouhamou, Nouara,Chiaroni, Angèle,Vedrenne, Emeline,Grimaud, Laurence,Six, Yvan
, p. 8878 - 8898 (2008/12/21)
A range of amides fitted with (E) or (Z) disubstituted alkene groups were prepared and evaluated in intramolecular Kulinkovich-de Meijere reactions. The corresponding aminocyclopropanes were obtained with high diastereoselectivity. Good yields could be achieved with substrates bearing suitable substitutions at the olefin moieties.
