546-68-9 Usage
Reactions
Catalyst for the synthesis of acyclic epoxy alcohols and allylic epoxy alcohols.
Useful for diastereoselective reduction of alpha-fluoroketones.
Catalyzes the asymmetric allylation of ketones.
Reagent for the synthesis of cyclopropylamines from aryl and alkenyl nitriles.
Useful for racemic and/or enantioselective addition of nucleophiles to aldehydes, ketones and imines.
Catalytic intramolecular formal [3+2] cycloaddition.
Catalyst for the synthesis of cyclopropanols from esters and organomagnesium reagents
Chemical Properties
colourless to light yellow liquid
Uses
Different sources of media describe the Uses of 546-68-9 differently. You can refer to the following data:
1. Catalyst especially for asymmetric induction in organic syntheses; in preparation of nanosized TiO2. Complexing agent in sol-gel process.
2. Titanium(IV) isopropoxide is used as a precursor for the preparation of titanium and barium-strontium-titanate thin films. It is useful to make porous titanosilicates and potential ion-exchange materials for cleanup of radioactive wastes. It is an active component of Sharpless epoxidation as well as involved in the synthesis of chiral epoxides. In Kulinkovich reaction, it is involved as a catalyst in the preparation of cyclopropanes.
Definition
ChEBI: Titanium(IV) isopropoxide is a titanium coordination entity consisting of a titanium(IV) cation with four propan-2-olate anions as counterions.
General Description
Tetraisopropyl titanate appears as a water-white to pale-yellow liquid with an odor like isopropyl alcohol. About the same density as water. Vapors heavier than air.
Air & Water Reactions
Highly flammable. Fumes in air. Soluble in water. Decomposes rapidly in water to form flammable isopropyl alcohol.
Reactivity Profile
Metal alkyls, such as TETRAISOPROPYL TITANATE, are reducing agents and react rapidly and dangerously with oxygen and with other oxidizing agents, even weak ones. Thus, they are likely to ignite on contact with alcohols.
Health Hazard
Inhalation or contact with material may irritate or burn skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
Flammability and Explosibility
Flammable
Purification Methods
Dissolve it in dry *C6H6 , filter if a solid separates, evaporate and fractionate. It is hydrolysed by H2O to give solid Ti2O(iso-OPr)2 m ca 48o. [Bradley et al. J Chem Soc 2027, 1952, Bradley et al. J Chem Soc 469 1957, Beilstein 1 II 328, 1 IV 1469S.]
Check Digit Verification of cas no
The CAS Registry Mumber 546-68-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,4 and 6 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 546-68:
(5*5)+(4*4)+(3*6)+(2*6)+(1*8)=79
79 % 10 = 9
So 546-68-9 is a valid CAS Registry Number.
InChI:InChI=1/4C3H8O.Ti/c4*1-3(2)4;/h4*3-4H,1-2H3;
546-68-9Relevant articles and documents
Ferroelectric films of Ba0.7-0.8Sr0.2-0.3TiO 3 solid solutions deposited from carboxylate solutions
Tomashpol'skii,Golikova,Rybakova
, p. 945 - 948 (2002)
Ferroelectric films of Ba0.7-0.8Sr0.2-0.3TiO 3 solid solutions 2-3 μm in thickness were deposited onto platinum substrates from carboxylate solutions and characterized by dielectric measurements at 1000 Hz: tC = 15-16°C, ε20 > 1000, tan δ = 0.04-0.06 in the range 10-100°C. The controllability coefficient of the films in a dc electric field between 36 and 42°C is 1.6.
Aggrawal, M.,Mehrotra, R. C.
, p. 845 - 852 (1985)
Blandy, Claudine,Gervais, Daniele
, p. 79 - 82 (1981)
Preparation method of titanium tetraisopropoxide
-
Paragraph 0047-0088, (2020/11/26)
The invention relates to a preparation method of titanium tetraisopropoxide. The preparation method comprises the following steps: mixing a solvent, titanium tetrachloride and isopropanol to prepare amixed reaction system; and adding dialkylamine into the mixed reaction system to react, and carrying out aftertreatment on the obtained reactant to prepare the titanium tetraisopropoxide. The preparation method comprises the following steps: taking titanium tetrachloride and isopropanol as raw materials and adding dialkylamine into the mixed reaction system, wherein the dialkylamine can effectively absorb HCl generated by the reaction of the mixed reaction system, the reaction is promoted, meanwhile, impurities can be prevented from being generated, the high-purity titanium tetraisopropoxidecan be prepared through simple post-treatment, and the yield is high.
Dithiocarbamate complexes of Ti(IV) alkoxides: Synthesis, characterization, and electrochemistry
Donzelli, Alberto,Potvin, Pierre G.
, p. 4171 - 4178 (2009/09/26)
Isopropoxy- and ferf-butoxy-fr;'s(dithiocarbamato)titanium(IV) complexes of five dithiocarbamate ligands were prepared and characterized by LDI-MS, 1H NMR, 13C NMR, and elemental analysis, as well as by crystallographic determination of two examples. Both