1064288-29-4 Usage
General Description
(E)-1-(3-hydroxy-2,4-bis(MorpholinoMethyl)phenyl)-3-(pyridin-2-yl)prop-2-en-1-one is a chemical compound with a complex molecular structure. It consists of a phenyl ring with two morpholinomethyl groups, a pyridinyl group, and a propenone moiety. The compound also contains a hydroxyl group attached to the phenyl ring, giving it a hydrophilic character. The presence of the pyridinyl group suggests potential biological activity, as pyridine derivatives are known to exhibit various pharmacological properties. The intricate structure of this compound indicates potential applications in medicinal chemistry, particularly in drug discovery and development. Further research is needed to fully understand the chemical and biological properties of this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 1064288-29-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,6,4,2,8 and 8 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1064288-29:
(9*1)+(8*0)+(7*6)+(6*4)+(5*2)+(4*8)+(3*8)+(2*2)+(1*9)=154
154 % 10 = 4
So 1064288-29-4 is a valid CAS Registry Number.
1064288-29-4Relevant articles and documents
Design, synthesis, and biological evaluation of Mannich bases of heterocyclic chalcone analogs as cytotoxic agents
Reddy, M. Vijaya Bhaskar,Su, Chung-Ren,Chiou, Wen-Fei,Liu, Yi-Nan,Chen, Rosemary Yin-Hwa,Bastow, Kenneth F.,Lee, Kuo-Hsiung,Wu, Tian-Shung
, p. 7358 - 7370 (2008/12/22)
The chalcone skeleton (1,3-diphenyl-2-propen-1-one) is a unique template that is associated with various biological activities. We synthesized Mannich bases of heterocyclic chalcones (9-47) using a one-step Claisen-Schmidt condensation of heterocyclic aldehydes with Mannich bases of acetophenones, and tested the target compounds for cytotoxicity against three human cancer cell lines (prostate, PC-3; breast, MCF-7; nasopharynx, KB) and a multi-drug resistant subline (KB-VIN). Out of the 39 chalcones synthesized, 31 compounds showed potent activity against at least one cell line with IC50 values ranging from 0.03 to 3.80 μg/mL. Structure-activity relationships (SAR) are also discussed.