106464-80-6Relevant academic research and scientific papers
1,4-DIASTEREOSELECTIVITY IN THE ADDITION OF ALLYLSTANNANES TO 1-ALKYL-2-OXOCYCLOHEX-3-ENEACETIC ACID METHYL ESTERS
Mobilio, Dominick,Lange, Barbara De
, p. 1483 - 1486 (2007/10/02)
Cyclohexanones 1 were allowed to react with allyltrimethylsilane and three allyltributylstannanes in the presence of titanium tetrachloride.Products 2 and 3 were formed in ratios ranging from 7:1 to 26:1 (2:3).Ratios resulting from the use of other Lewis acids support 4 as an intermediate which accounts for the observed stereoselectivity.
