1064656-49-0

Basic information

• Product Name: 1-benzyl-3-ethyl-3,4-dihydro-1H-2,1-benzothiazin-4-one 2,2-dioxide
• Synonyms: 1-benzyl-3-ethyl-3,4-dihydro-1H-2,1-benzothiazin-4-one 2,2-dioxide
• CAS NO: 1064656-49-0
• Molecular Weight: 315.393
• Mol File: 1064656-49-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-benzyl-3-ethyl-3,4-dihydro-1H-2,1-benzothiazin-4-one 2,2-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-3-ethyl-3,4-dihydro-1H-2,1-benzothiazin-4-one 2,2-dioxide(1064656-49-0)
• EPA Substance Registry System: 1-benzyl-3-ethyl-3,4-dihydro-1H-2,1-benzothiazin-4-one 2,2-dioxide(1064656-49-0)

Safety Data

• Hazardous Substances Data: 1064656-49-0(Hazardous Substances Data)

Upstream product

• 552-16-9 ortho-nitrobenzoic acid 
• 14533-63-2 1-propanesulfonic acid sodium salt 
• 100-51-6 benzyl alcohol 
• 10147-36-1 n-propanesulfonyl chloride 
• 5284-66-2 propanesulfonic acid 
• 1064657-94-8 methyl N-benzyl-N-(1-propanesulfonyl)anthranilate 

Relevant articles and documents

A solid-phase synthetic method for 3,4-dihydro-1H-2,1-benzothiazin-4-one 2,2-dioxide derivatives

Utilizing polymer-bound anthranilic acid derivatives, we were able to obtain 3,4-dihydro-1H-2,1-benzothiazine-4-one 2,2-dioxide derivatives through N-methanesulfonylation by use of sulfonyl chloride, sulfonic acid, or sodium sulfonate, N-alkylation under Mitsunobu condition, and the cyclative cleavage in 8-52% five-step overall isolated yields and 91-99% purities from Wang resin. The reactions on solid phase were monitored by on-bead ATR-FTIR spectroscopic method and checked by help of solution-phase model experiments.