5284-66-2Relevant academic research and scientific papers
An efficient catalyst for low temperature solid-phase cyclization of poly(o-hydroxyamide)
Toyokawa, Fumihiro,Fukukawa, Ken-Ichi,Shibasaki, Yuji,Ueda, Mitsuru
, p. 1342 - 1343 (2004)
An efficient acid catalyst for the low-temperature solid-phase cyclization of poly(o-hydroxyamide) (PHA) has been found. Thermal cyclization of PHA into poly(benzoxazole) (PBO) proceeded quantitatively at 250°C in 10min in the presence of 10 wt % of a photoacitve compound, (5-propylsulfonyloxyimino-5H- thiophen-2-ylidene)-2-(methylphenyl)-acetonitrile (PTMA).
Evaluation of O-alkyl and aryl sulfonyl aromatic and heteroaromatic amidoximes as novel potent DNA photo-cleavers
Papastergiou,Perontsis,Gritzapis,Koumbis,Koffa,Psomas,Fylaktakidou
, p. 351 - 360 (2016/03/22)
Several stable O-alkyl and aryl sulfonyl conjugated p-nitro-Ph and o-, m-, p-pyridine N′-hydroxy imidamides, were subjected to UV irradiation at 312 nm with supercoiled circular plasmid DNA pBluescript KS II. The generated amidinyl and sulfonyloxyl radicals led to effective DNA photo-cleavage. Both alkyl and aryl sulfonyl derivatives were active and the order p-pyridine > p-nitro-Ph > o-pyridine > m-pyridine was schematized for the N′-hydroxy imidamides moiety. Calf thymus-DNA affinity studies which comprised UV interactions, viscosity experiments and competitive studies with ethidium bromide showed good to excellent affinity of the compounds. These properties revealed sulfonyl amidoximes as novel effective DNA-photo-cleavers and may serve in the discovery of new leads for "on demand" biotechnological and medical applications.
Marine bacteria from the Roseobacter clade produce sulfur volatiles via amino acid and dimethylsulfoniopropionate catabolism
Brock, Nelson L.,Menke, Markus,Klapschinski, Tim A.,Dickschat, Jeroen S.
supporting information, p. 4318 - 4323 (2014/06/23)
Dimethylsulfoniopropionate (DMSP) is a versatile sulfur source for the production of sulfur-containing secondary metabolites by marine bacteria from the Roseobacter clade. 34S-labelled DMSP and cysteine, and several DMSP derivatives with modified S-alkyl groups were synthesised and used in feeding experiments that gave insights into the biosynthesis of sulfur volatiles from these bacteria. the Partner Organisations 2014.
Selective oxidation reactions of diaryl- and dialkyldisulfides to sulfonic acids by CH3ReO3/hydrogen peroxide
Ballistreri, Francesco P.,Tomaselli, Gaetano A.,Toscano, Rosa M.
experimental part, p. 6231 - 6232 (2010/01/11)
Diaryl- and dialkyl disulfides were oxidized in acetonitrile at 20 °C by CH3ReO3/H2O2 oxidant system to yield selectively the corresponding sulfonic acids in short reaction times and in high yields.
Novel benzothiepines having activity as inhibitors of lleal bile acid transport and taurocholate uptake
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, (2008/06/13)
Provided are novel benzothiepines, derivatives, and analogs thereof; pharmaceutical compositions containing them; and methods of using these compounds and compositions in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions such as those associated with atherosclerosis or hypercholesterolemia, in mammals.
Novel benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
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, (2008/06/13)
Provided are novel benzothiepines, derivatives, and analogs thereof; pharmaceutical compositions containing them; and methods of using these compounds and compositions in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions such as those associated with atherosclerosis or hypercholesterolemia, in mammals.
Benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
-
, (2008/06/13)
Provided are novel benzothiepines, derivatives, and analogs thereof; pharmaceutical compositions containing them; and methods of using these compounds and compositions in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions such as those associated with atherosclerosis or hypercholesterolemia, in mammals.
Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors
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, (2008/06/13)
Provided are novel benzothiepines, derivatives, and analogs thereof; pharmaceutical compositions containing them; and methods of using these compounds and compositions in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions such as those associated with atherosclerosis or hypercholesterolemia, in mammals. Also provided are compositions and methods for combination therapy employing ileal bile acid transport inhibitors and EG Co-A reductase inhibitors for the treatment of hyperlipidemic conditions.
Substituted 5-aryl-benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
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, (2008/06/13)
Provided are novel benzothiepines, derivatives, and analogs thereof; pharmaceutical compositions containing them; and methods of using these compounds and compositions in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions such as those associated with atherosclerosis or hypercholesterolemia, in mammals.
Benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
-
, (2008/06/13)
Provided are novel benzothiepines, derivatives, and analogs thereof; pharmaceutical compositions containing them; and methods of using these compounds and compositions in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions such as those associated with atherosclerosis or hypercholesterolemia, in mammals.
