106473-33-0Relevant academic research and scientific papers
Palladium-catalyzed approach to primary amides using nongaseous precursors
Nielsen, Dennis U.,Taaning, Rolf H.,Lindhardt, Anders T.,Gogsig, Thomas M.,Skrydstrup, Troels
supporting information; experimental part, p. 4454 - 4457 (2011/10/05)
A simple protocol is reported for the preparation of primary aryl amides under Pd-catalyzed carbonylation chemistry applying a two-chamber system with crystalline and nontransition metal based sources of carbon monoxide and ammonia. The method is suitable for the synthesis of a number of primary amides with good functional group tolerance. Incorporation of 13CO into the primary amide group was also found to be effective making this approach useful for accessing carbon isotope labeled derivatives.
Preparation of enamides via palladium-catalyzed amidation of enol tosylates
Klapars, Artis,Campos, Kevin R.,Chen, Cheng-Yi,Volante, Ralph P.
, p. 1185 - 1188 (2007/10/03)
(Chemical Equation Presented) A Pd-catalyzed coupling of enol tosylates and amides has been developed. Ligand screening revealed dipf as the most general ligand for this transformation. A variety of enol tosylates were coupled to an array of enamides in 5
