106508-97-8

Basic information

• Product Name: Ethyl 4'-methylbiphen-4-ylcarboxylate
• Synonyms: Ethyl 4'-methylbiphen-4-ylcarboxylate;4'-Methyl-[1,1'-biphenyl]-4-carboxylic acid ethyl ester
• CAS NO: 106508-97-8
• Molecular Formula: C₁₆H₁₆O₂
• Molecular Weight: 240
• Mol File: 106508-97-8.mol
• Article Data: 5

Chemical Properties

• Melting Point: 78-79℃
• Appearance: /
• CAS DataBase Reference: Ethyl 4'-methylbiphen-4-ylcarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 4'-methylbiphen-4-ylcarboxylate(106508-97-8)
• EPA Substance Registry System: Ethyl 4'-methylbiphen-4-ylcarboxylate(106508-97-8)

Safety Data

• Hazardous Substances Data: 106508-97-8(Hazardous Substances Data)

Upstream product

• 6952-59-6 3-cyanobromobenzene 
• 5798-75-4 Ethyl 4-bromobenzoate 
• 623-00-7 4-bromobenzenecarbonitrile 
• 2042-37-7 o-cyanobromobenzene 
• 51934-41-9 4-iodobenzoic acid ethyl ester 
• 5720-05-8 4-methylphenylboronic acid 
• 1160723-48-7 N-benzyl-N-((4-methoxyphenyl)ethynyl)-4-methylbenzenesulfonamide 
• 609769-63-3 N-benzyl-N-(p-toluenesulfonyl)-2-phenylethynylamine 
• 1174638-52-8 N-benzyl-4-methyl-N-(prop-1-yn-1-yl)benzenesulfonamide 
• 496922-59-9 N-benzyl-N-(1-octynyl)-p-toluenesulfonamide 
• 348-06-1 p-carboethoxybenzenediazonium tetrafluoroborate 
• 108-88-3 toluene 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 7335-27-5 ethyl 4-chlorobenzoate 

Downstream Products

• 49742-56-5 methyl 4-(4-tolyl)benzoate 
• 106509-00-6 C₆₆H₆₆N₂O₁₄S₂ 

Relevant articles and documents

Palladium-Catalyzed Three-Component Coupling of Ynamides

A palladium-catalyzed regioselective three-component coupling of ynamides was developed. The reaction proceeded smoothly to furnish the desired products when carried out at 70 °C in acetonitrile/water with potassium carbonate in the presence of 2.5 mol percent Pd2(dba)3·CHCl3 without a ligand. Various iodides and boronic acids were used in this reaction, and a carbon-carbon bond was formed with satisfactory regioselectivity from the ynamides.

Nickel-catalyzed cross-coupling of non-activated or functionalized aryl halides with aryl grignard reagents

Figure Presented New nickel complexes can efficiently catalyze cross-coupling of unactivated and deactivated aryl chlorides and fluorides with aryl Grignard reagents. The reaction can tolerate functional groups in aryl chlorides with or without the aid of additives, depending on the substrates (see scheme).

A new palladium catalyzed protocol for atom-efficient cross-coupling reactions of?triarylbismuths with aryl halides and triflates

A new palladium catalyzed protocol for an atom-efficient cross-coupling reaction of triarylbismuths with aryl halides and triflates has been described. The palladium catalytic system with Cs2CO3 base was found to be very efficient in DMA solvent to furnish excellent yields of cross-coupled functionalized biaryls in short reaction times.