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Tert-butyl 2,4-dichloro-8,9-dihydro-5H-pyrimido[4,5-d]azepine-7(6H)-carboxylate is a complex organic compound characterized by its molecular formula C15H19Cl2N3O2. It is a derivative of pyrimidoazepine, featuring two chlorine atoms attached to the 2nd and 4th carbon atoms of the pyrimidoazepine ring. Tert-butyl 2,4-dichloro-8,9-dihydro-5H-pyrimido[4,5-d]azepine-7(6H)-carboxylate also includes a tert-butyl group at the 7th carbon atom and a carboxylate group attached to the nitrogen atom within the pyrimidoazepine ring. Its intricate structure and properties render it a valuable asset in the realms of organic synthesis and pharmaceutical research, particularly for the study of reactivity and behavior of pyrimidoazepine derivatives.

1065114-27-3

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  • tert-Butyl 2,4-dichloro-5,6,8,9-tetrahydropyrimido[4,5-d]azepine-7-carboxylate

    Cas No: 1065114-27-3

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1065114-27-3 Usage

Uses

Used in Organic Synthesis:
Tert-butyl 2,4-dichloro-8,9-dihydro-5H-pyrimido[4,5-d]azepine-7(6H)-carboxylate is used as a key intermediate in organic synthesis for the preparation of various complex organic molecules. Its unique structural features allow for versatile chemical reactions, facilitating the creation of a wide range of compounds with potential applications in different fields.
Used in Pharmaceutical Research:
In the pharmaceutical industry, Tert-butyl 2,4-dichloro-8,9-dihydro-5H-pyrimido[4,5-d]azepine-7(6H)-carboxylate is utilized as a starting material for the development of new drugs. Its specific chemical properties make it a promising candidate for the synthesis of bioactive molecules with potential therapeutic effects. Researchers leverage its reactivity to explore novel drug candidates, particularly those targeting specific biological pathways or diseases.
Used in Chemical Education and Research:
Tert-butyl 2,4-dichloro-8,9-dihydro-5H-pyrimido[4,5-d]azepine-7(6H)-carboxylate also serves as an educational tool in chemical education and research settings. Its complex structure provides a platform for teaching and learning about organic chemistry, reaction mechanisms, and the synthesis of complex organic compounds. Additionally, it is employed in research to investigate the fundamental principles of organic chemistry and to develop new synthetic methodologies.

Check Digit Verification of cas no

The CAS Registry Mumber 1065114-27-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,6,5,1,1 and 4 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1065114-27:
(9*1)+(8*0)+(7*6)+(6*5)+(5*1)+(4*1)+(3*4)+(2*2)+(1*7)=113
113 % 10 = 3
So 1065114-27-3 is a valid CAS Registry Number.

1065114-27-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-Butyl 2,4-dichloro-5,6,8,9-tetrahydropyrimido-[4,5-d]azepine-7-carboxylate

1.2 Other means of identification

Product number -
Other names 2,4-Dichloro-5,6,8,9-tetrahydro-7H-pyrimido[4,5-d]azepine-7-carboxylic acid tert-butyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1065114-27-3 SDS

1065114-27-3Relevant articles and documents

PYRIMIDO [4, 5-D] AZEPINE DERIVATIVES AS 5-HT2C AGONISTS

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Page/Page column 169, (2008/12/04)

The present invention relates to compounds of formula (I): wherein R1, R2, R3a,R3b, R3c, R3d and R100 are as defined in the specification. These compounds act as 5-HT2C agonists.

BICYCLIC PYRIMIDINE DERIVATIVES

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Page/Page column 304, (2008/06/13)

[wherein m and n may be the same or different and each represents an integer of 1 to 3 wherein m + n is 4 or less; R1 represents NR4R5 (wherein R4 and R5 may be the same or different and each represents a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted aralkyl or the like); R2 represents the above Formula (II), Formula (IV) or the like; A represents a single bond, -C(=O)-, -SO2-, -OC(=O)- or the like; and R3 represents substituted or unsubstituted lower alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted aralkyl or the like]ψBicyclic pyrimidine derivatives represented by the above Formula (I), or quaternary ammonium salts thereof, or pharmaceutically acceptable salts thereof, or the like, are provided. These have anti-inflammatory activities or modulation activities on the functions of TARC and/or MDC and are useful for treating and/or preventing a disease which is related to T cells, such as an allergic disease, an autoimmune disease or transplant rejection.

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