106523-20-0Relevant academic research and scientific papers
4-cyano-7, 8-dihydroisoquinoline derivative as well as preparation method and application thereof
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Paragraph 0067, (2021/05/05)
The invention relates to the technical field of organic synthesis, in particular to a 4-cyano-7, 8-dihydroisoquinoline derivative as well as a preparation method and application thereof. According to the invention, symmetric and asymmetric dicyanomethylene-4H-pyran derivatives and secondary amine are used as raw materials, and a series of 4-cyano-7, 8-dihydroisoquinoline derivatives are prepared through ring opening and continuous ring closing reactions; and the reaction has the advantages of easily available raw materials, mild reaction conditions, wide substrate range, high yield and the like, is simple to operate, and avoids the defects of tedious steps, harsh reaction conditions, use of toxic and expensive metal catalysts and the like in conventional isoquinoline compound construction. The preparation method provides new possibilities for design and synthesis of isoquinoline molecules and application of the isoquinoline molecules in solid-state fluorescent materials.
Synthesis of new efficient laser dyes of red spectral range, the DCM analogs, based on 2-aryl-6-methyl-4H-pyrone
Ponomareva,Lugovskii,Lugovskii,Males,Komlev,Nifant'Ev
, p. 2310 - 2315 (2012/03/12)
A new method was developed for the synthesis of 2-aryl-6-methyl-4H-pyrones by the condensation of arylmethylketones with the acetoacetic ester ethylene ketal in the presence of sodium alkoxylate. New laser merocyanine dyes, the analogues of 4-dicyanomethylene-2-methyl-6-[(4-dimethylamino)styryl]-4H-pyran (DCM), were obtained based on the synthesized 2-aryl-4-pyrones. The dyes are characterized by high generation efficiency in the red spectral range.
