Welcome to LookChem.com Sign In|Join Free

CAS

  • or

106535-16-4

Post Buying Request

106535-16-4 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

106535-16-4 Usage

General Description

Methyl 2-(1H-1,2,4-triazol-1-yl)acetate is a chemical compound with the molecular formula C5H7N3O2. It is a clear, colorless liquid that is commonly used as a building block in organic synthesis, particularly in the pharmaceutical industry. METHYL 2-(1H-1,2,4-TRIAZOL-1-YL)ACETATE is known for its potential application as a fungicide, herbicide, and insecticide. It is also used in the manufacture of various pharmaceuticals and agrochemicals. Methyl 2-(1H-1,2,4-triazol-1-yl)acetate is an important intermediate in the production of a wide range of compounds, and it is known for its versatile reactivity and ability to participate in a variety of chemical reactions.

Check Digit Verification of cas no

The CAS Registry Mumber 106535-16-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,5,3 and 5 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 106535-16:
(8*1)+(7*0)+(6*6)+(5*5)+(4*3)+(3*5)+(2*1)+(1*6)=104
104 % 10 = 4
So 106535-16-4 is a valid CAS Registry Number.
InChI:InChI=1/C5H7N3O2/c1-10-5(9)2-8-4-6-3-7-8/h3-4H,2H2,1H3

106535-16-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name Methyl 2-(1H-1,2,4-triazol-1-yl)acetate

1.2 Other means of identification

Product number -
Other names methyl 2-(1,2,4-triazol-1-yl)acetate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:106535-16-4 SDS

106535-16-4Relevant articles and documents

Taming Ambident Triazole Anions: Regioselective Ion Pairing Catalyzes Direct N-Alkylation with Atypical Regioselectivity

Dale, Harvey J.A.,Hodges, George R.,Lloyd-Jones, Guy C.

, p. 7181 - 7193 (2019)

Controlling the regioselectivity of ambident nucleophiles toward alkylating agents is a fundamental problem in heterocyclic chemistry. Unsubstituted triazoles are particularly challenging, often requiring inefficient stepwise protection-deprotection strategies and prefunctionalization protocols. Herein we report on the alkylation of archetypal ambident 1,2,4-triazole, 1,2,3-triazole, and their anions, analyzed by in situ 1H/19F NMR, kinetic modeling, diffusion-ordered NMR spectroscopy, X-ray crystallography, highly correlated coupled-cluster computations [CCSD(T)-F12, DF-LCCSD(T)-F12, DLPNO-CCSD(T)], and Marcus theory. The resulting mechanistic insights allow design of an organocatalytic methodology for ambident control in the direct N-alkylation of unsubstituted triazole anions. Amidinium and guanidinium receptors are shown to act as strongly coordinating phase-transfer organocatalysts, shuttling triazolate anions into solution. The intimate ion pairs formed in solution retain the reactivity of liberated triazole anions but, by virtue of highly regioselective ion pairing, exhibit alkylation selectivities that are completely inverted (1,2,4-triazole) or substantially enhanced (1,2,3-triazole) compared to the parent anions. The methodology allows direct access to 4-alkyl-1,2,4-triazoles (rr up to 94:6) and 1-alkyl-1,2,3-triazoles (rr up to 99:1) in one step. Regioselective ion pairing acts in effect as a noncovalent in situ protection mechanism, a concept that may have broader application in the control of ambident systems.

Preparing method of triazole compound

-

Paragraph 0049-0053, (2019/06/12)

The invention discloses a preparing method of a triazole compound. The synthesis process includes the following step of conducting the substitution reaction on the main raw material (a compound shownin the formula III) and a compound shown in the formula

Efficient synthesis and in vitro antifungal activity of 1H-benzimidazol-1-yl acetates/propionates containing 1H-1,2,4-triazole moiety

Zhang, Pei Zhi,Zhou, Shao Fang,Li, Tian Ren,Jiang, Lin

, p. 1381 - 1384 (2013/02/22)

A series of novel 1H-benzimidazol-1-yl acetates and 1H-benzimidazol-1-yl propionates containing 1H-1,2,4-triazole moiety were synthesized under microwave irradiation by multi-step reactions, in yields of 87-94%. Their in vitro antifungal activities against Botrytis cinerea and Sclerotinia sclerotiorum were evaluated by mycelial growth rate method. All the target compounds exhibit high activities against B. cinerea with the EC50 values of 7.96-21.74 μg/mL, higher than that of carbendazim.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 106535-16-4