106565-23-5Relevant academic research and scientific papers
Chelation- and Nonchelation-Controlled Reductions of β-Dicarbonyl Compounds to 1,3-Diols with Three Chiral Centers
Barluenga, Jose,Resa, Julio G.,Olano, Bernardo,Fustero, Santos
, p. 1425 - 1428 (1987)
1,3-Diols 5 with three chiral centers are easily obtained, as a diastereoisomer mixture, by reduction of β-dicarbonyl compounds 4 with lithium aluminum hydrides.The diastereoisomer ratio depends largely on the solvent and the nature of the reducing agent.
