106578-67-0

Upstream product

• 106578-69-2 1-phenyl-1-(N-phenylamino)-4,4,4-trifluoro-1-buten-3-one 
• 74-89-5 methylamine 
• 106578-65-8 (Z)-4-Amino-1,1,1-trifluoro-4-phenyl-but-3-en-2-one 
• 144864-93-7 1-phenyl-4,4,4-trifluorobutane-1,3-dione 
• 127223-87-4 (E)-1,1,1-Trifluoro-4-methylsulfanyl-4-phenyl-but-3-en-2-one 

Downstream Products

• 106578-69-2 1-phenyl-1-(N-phenylamino)-4,4,4-trifluoro-1-buten-3-one 

Relevant academic research and scientific papers

Interaction of fluoroalkyl-containing β-diketones with amines

The composition of products of the interaction of asymmetric fluoroalkyl-containing β-diketones with amines was studied. Mixtures of regioisomeric β-aminovinylketones and products of cleavage and secondary condensation are formed, depending on the temperature, the solvent, the nature of the fluorinated and nonfluorinated substituents in the β-diketone, and the basicity of the amine. The major product is a β-aminovinylketone in which the NH2 group is removed from the fluoroalkyl substituent. No β-aminovinylimines, products of condensation involving two electrophilic centers, were observed.

O-N, S-N AND N-N EXCHANGE REACTIONS AT OLEFINIC CARBON ATOMS: FACILE SYNTHETIC METHOD FOR β-TRIFLUOROACETYLVINYLAMINES

β-Trifluoroacetylvinyl ethers 1 and sulfides 2 react easily with various amines at room temperature to give β-trifluoroacetylvinylamines 3 in excellent yields.This O-N and S-N exchange reaction can be extended to N-N exchange reaction.