106584-05-8Relevant articles and documents
Efficient Selenium-Catalyzed Selective C(sp3)?H Oxidation of Benzylpyridines with Molecular Oxygen
Jin, Weiwei,Zheng, Poonnapa,Wong, Wing-Tak,Law, Ga-Lai
supporting information, p. 1588 - 1593 (2017/05/05)
An efficient selenium-catalyzed direct oxidation of benzylpyridines in aqueous DMSO has been successfully developed by using molecular oxygen as the oxidant. A variety of benzoylpyridines with broad functional group tolerance were obtained in modest to excellent yields and with exclusive chemoselectivity. (Figure presented.).
Versatile C(sp2)?C(sp3) Ligand Couplings of Sulfoxides for the Enantioselective Synthesis of Diarylalkanes
Dean, William M.,?iau?iulis, Mindaugas,Storr, Thomas E.,Lewis, William,Stockman, Robert A.
, p. 10013 - 10016 (2016/08/16)
The reaction of chiral (hetero)aryl benzyl sulfoxides with Grignard reagents affords enantiomerically pure diarylalkanes in up to 98 % yield and greater than 99.5 % enantiomeric excess. This ligand coupling reaction is tolerant to multiple substitution patterns and provides access to diverse areas of chemical space in three operationally simple steps from commercially available reagents. This strategy provides orthogonal access to electron-deficient heteroaromatic compounds, which are traditionally synthesized by transition metal catalyzed cross-couplings, and circumvents common issues associated with proto-demetalation and β-hydride elimination.
REARRANGEMENT OF 2-HETARYLALKYLPYRIDINIUM SALTS
Rumyantsev, A. N.,Terenin, V. I.,Yudin, L. G.
, p. 300 - 303 (2007/10/02)
The rearrangement of 2-thienyl- and 2-furylalkylpyridinium salts to the corresponding anilines by the action of methylammonium sulfites has been studied.It has been shown that the rearrangement of these salts is accompanied in many cases by the formation of phenols and dealkylation products.The influence of the length of the alkyl chain between the heterocyclic rings on the ratio of the rearrangement products has been investigated.