106595-93-1

Usage

Chemical compound

2-[4-(dimethylamino)phenyl]benzo[d]isothiazol-3(2H)-one

Unique structure

Contains a benzene ring fused to an isothiazole ring, with a dimethylamino group attached to a phenyl ring

Uses

Used as a precursor for the synthesis of pharmaceuticals and agrochemicals in organic chemistry

Enzyme inhibition

Shows potential as an inhibitor of certain enzymes

Medicinal uses

Studied for potential medicinal applications

Photoconductive material

Investigated for potential use in electronics

Research

Further studies needed to understand properties and potential applications

Upstream product

• 81223-44-1 methyl 4-fluoro-2-sulfanyl-benzoate 
• 99-98-9 4-amino-N,N-dimethylaniline 
• 1622392-93-1 C₁₅H₁₆N₂OS 
• 2634-33-5 1,2-benzisothiazolin-3-one 
• 698-70-4 4-Iodo-N,N-dimethylaniline 

Relevant academic research and scientific papers

Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1

We report the discovery and characterization of a series of benzoisothiazolone inhibitors of PHOSPHO1, a newly identified soluble phosphatase implicated in skeletal mineralization and soft tissue ossification abnormalities. High-throughput screening (HTS)

BENZOISOTHIAZOLONES AS INHIBITORS OF PHOSPHOMANNOSE ISOMERASE

The disclosure provides new compounds and compositions thereof, and methods for treating or ameliorating a disorder relating to CDG-Ia. In particular, the disclosure provides benzoisothiazolone inhibitors of PMI, which have been synthesized and their abil

Potent, selective, and orally available benzoisothiazolone phosphomannose isomerase inhibitors as probes for congenital disorder of glycosylation Ia

We report the discovery and validation of a series of benzoisothiazolones as potent inhibitors of phosphomannose isomerase (PMI), an enzyme that converts mannose-6-phosphate (Man-6-P) into fructose-6-phosphate (Fru-6-P) and, more importantly, competes wit