106600-24-2Relevant academic research and scientific papers
Ni/Photoredox-Dual-Catalyzed Functionalization of 1-Thiosugars
Zhu, Mingxiang,Dagousset, Guillaume,Alami, Mouad,Magnier, Emmanuel,Messaoudi, Samir
, p. 5132 - 5137 (2019)
A general protocol for functionalization of glycosyl thiols has been reported. This protocol is based on a single-electron Ni/photoredox dual-catalyzed cross coupling between 1-thiosugars and a broad range of aryl bromides and iodides as well as alkenyl and alkynyl halides. This base-free method gives access to a series of functionalized thioglycosides in moderate to excellent yields with a perfect control of the anomeric configuration. Moreover, it has been shown that this methodology may be transposed successfully to the continuous-flow photoredox chemistry.
