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N-Sulphamyl-3-chloropropionamidine hydrochloride is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

106649-95-0

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106649-95-0 Usage

Uses

N-Sulphamyl-3-chloropropionamidine Hydrochloride is used in preparation Famotidine.

Check Digit Verification of cas no

The CAS Registry Mumber 106649-95-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,6,4 and 9 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 106649-95:
(8*1)+(7*0)+(6*6)+(5*6)+(4*4)+(3*9)+(2*9)+(1*5)=140
140 % 10 = 0
So 106649-95-0 is a valid CAS Registry Number.
InChI:InChI=1/C3H8ClN3O2S.ClH/c4-2-1-3(5)7-10(6,8)9;/h1-2H2,(H2,5,7)(H2,6,8,9);1H

106649-95-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-chloro-N'-sulfamoylpropanimidamide

1.2 Other means of identification

Product number -
Other names N-SULPHAMYL-3-CHLOROPROPIONAMIDINE HCL

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:106649-95-0 SDS

106649-95-0Downstream Products

106649-95-0Relevant academic research and scientific papers

A process for the preparation of N-sulfamyl-propionamidine derivatives

-

, (2008/06/13)

N-sulfamyl-propionamidine derivatives are prepared by the reaction of 3-substituted-propionitriles with an oxonium hydrochloride, preferably of 1,4-dioxane, in the presence of sulfamide in a close system at pressures between 0.5 kg/cm and 4.0 kg/cm. These compounds are useful in the preparation of famotidine, an anti-ulcer agent.

Process for the preparation of N-sulfamyl-3-(2-guanidino-thiazol-4-methylthio)-propionamidine

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, (2008/06/13)

The invention relates to a new process for the preparation of N-sulfamyl-3-(2-guanidinothiazol-4-yl-methylthio)-propionitrile (famotidine) of the formula (I) STR1 by S-alkylation of 2-guanidino-thiazol-4-yl-methanethiol obtained from S-(2-guanidino-thiazol-4-yl-methyl)-isothiourea dihydrochloride of the formula (III) STR2 by in situ treatment with a base, which comprises carrying out S-alkylation with a N-sulfamyl-3-halopropionamidine of the formula (II) STR3 wherein X stands for halogen.

N-sulfamyl-3-halopropionamidines

-

, (2008/06/13)

The invention relates to new propionamidine derivatives of formula (I) STR1 wherein X is halogen, and to a process for their preparation. According to the invention compounds of the formula (I) are prepared by reacting a 3-halopropionitrile of the formula (III) STR2 wherein X is as defined above, with sulfamide of the formula (II) STR3 in the presence of a hydrogen halide. Compounds of the formula (I) are useful intermediates in the preparation of famotidine.

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