106651-81-4

Basic information

• Product Name: 2-Methyl-5-chloromethylpyridine hydrochloride
• Synonyms: 2-Methyl-5-chloromethylpyridine hydrochloride;3-Chloromethyl-6-methylpyridine hydrochloride;5-Chloromethyl-2-methylpyridine hydrochloride;5-(CHLOROMETHYL)-2-METHYLPYRIDINEHCL
• CAS NO: 106651-81-4
• Molecular Formula: C₇H₈ClN*ClH
• Molecular Weight: 178.06
• Mol File: 106651-81-4.mol
• Article Data: 6

Chemical Properties

• Melting Point: 133-135 °C
• Boiling Point: 255.4 °C at 760 mmHg
• Flash Point: 108.3 °C
• Appearance: /
• Vapor Pressure: 0.0129mmHg at 25°C
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-Methyl-5-chloromethylpyridine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methyl-5-chloromethylpyridine hydrochloride(106651-81-4)
• EPA Substance Registry System: 2-Methyl-5-chloromethylpyridine hydrochloride(106651-81-4)

Safety Data

• Hazardous Substances Data: 106651-81-4(Hazardous Substances Data)

Usage

General Description

2-Methyl-5-chloromethylpyridine hydrochloride is a chemical compound with the molecular formula C7H8ClN·HCl. It is a pyridine derivative with a methyl group and a chlorine atom attached to the aromatic ring. 2-Methyl-5-chloromethylpyridine hydrochloride is commonly used in the synthesis of pharmaceuticals, agrochemicals, and dyes. It has also been studied for its potential as an anti-cancer agent. 2-Methyl-5-chloromethylpyridine hydrochloride is typically in the form of a white to off-white crystalline solid and is soluble in water. It is important to handle this chemical with care due to its potential to cause skin and eye irritation.

InChI:InChI=1/C7H8ClN.ClH/c1-6-2-3-7(4-8)5-9-6;/h2-3,5H,4H2,1H3;1H

Upstream product

• 5470-70-2 Methyl 6-methylnicotinate 
• 34107-46-5 6-methyl-3-pyridinemethanol 

Downstream Products

• 582303-24-0 dimethyl α-(4-tert-butyldimethylsilyloxy-3-methoxy-5-methylphenyl)-β-(5-(2-methylpyridyl))ethylphosphonate 
• 582303-14-8 diethyl α-(4-tert-butyldimethylsilyloxy-3-methoxy-5-methylphenyl)-β-(5-(2-methylpyridyl))ethyl-phosphonate 
• 543697-26-3 5-[(2R,3R,4S,5R,6R)-6-[2-(1-Benzenesulfonyl-1H-indol-3-yl)-ethoxy]-4,5-bis-benzyloxy-3-(6-methyl-pyridin-3-ylmethoxy)-tetrahydro-pyran-2-ylmethoxy]-pentylamine 
• 543697-52-5 3-{2-[(2R,3R,4S,5R,6R)-6-(5-Azido-pentyloxymethyl)-3,4-bis-benzyloxy-5-(6-methyl-pyridin-3-ylmethoxy)-tetrahydro-pyran-2-yloxy]-ethyl}-1-benzenesulfonyl-1H-indole 
• 52426-66-1 5-(chloromethyl)-2-methylpyridine 

Relevant articles and documents

INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASE

Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1 -mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.

SUBSTITUTED N-(1H-INDAZOL-4-YL)IMIDAZO[1,2-a]PYRIDINE-3-CARBOXAMIDE COMPOUNDS AS TYPE III RECEPTOR TYROSINE KINASE INHIBITORS

Compounds of Formula I: and pharmaceutically acceptable salts thereof in which R1, R2, R3, R4, R5 and R6 have the meanings given in the specification, are inhibitors of cFMS and are useful in the treatment of fibrosis, bone-related diseases, cancer, autoimmune disorders, inflammatory diseases, cardiovascular diseases, pain and burns in a mammal

Alpha-substituted arylalkyl phosphonate derivatives

The present invention relates to novel α-substituted arylalkylphosphonate derivatives and their uses for lowering plasma levels of apo (a), Lp(a), apo B, apo B associated lipoproteins (low density lipoproteins and very low density lipoproteins) and for lo