34107-46-5Relevant articles and documents
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Schmitz,Schunack
, p. 359,363 (1975)
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An Open Drug Discovery Competition: Experimental Validation of Predictive Models in a Series of Novel Antimalarials
?eren, Mario,Aithani, Laksh,Anderson, Mark,Cardoso-Silva, Jonathan,Cincilla, Giovanni,Conduit, Gareth J.,Galushka, Mykola,Guan, Davy,Hallyburton, Irene,Irwin, Benedict W. J.,Kirk, Kiaran,Lehane, Adele M.,Lindblom, Julia C. R.,Lui, Raymond,Matthews, Slade,McCulloch, James,Motion, Alice,Ng, Ho Leung,Robertson, Murray N.,Spadavecchio, Vito,Tatsis, Vasileios A.,Todd, Matthew H.,Tse, Edwin G.,Van Hoorn, Willem P.,Wade, Alexander D.,Whitehead, Thomas M.,Willis, Paul
supporting information, p. 16450 - 16463 (2021/11/24)
The Open Source Malaria (OSM) consortium is developing compounds that kill the human malaria parasite, Plasmodium falciparum, by targeting PfATP4, an essential ion pump on the parasite surface. The structure of PfATP4 has not been determined. Here, we des
Iron catalysed selective reduction of esters to alcohols
Tamang, Sem Raj,Cozzolino, Anthony F.,Findlater, Michael
supporting information, p. 1834 - 1838 (2019/02/20)
The reaction of (dppBIAN)FeCl2 with 3 equivalents of n-BuLi affords a catalytically active anionic Fe complex; the nature of the anionic complex was probed using EPR and IR experiments and is proposed to involve a dearomatized, radical, ligand scaffold. This complex is an active catalyst for the hydrosilylation of esters to afford alcohols; loadings as low as 1 mol% were employed.
Modular Route to Azaindanes
Huang, Qi,Zard, Samir Z.
supporting information, p. 3895 - 3898 (2017/07/26)
A convergent radical based route to azaindanes is described, relying on the degenerative addition transfer of various substituted S-(pyridylmethyl)-O-ethyl dithiocarbonates (xanthates) to functional alkenes followed by radical cyclization onto the pyridine ring activated by protonation with trifluoroacetic acid. In one case, a richly decorated cyclohepta[b]pyridine could be assembled swiftly by allowing the first adduct to N-phenylmaleimide to undergo addition to N-allylphthalimide prior to cyclization.
