106655-98-5Relevant academic research and scientific papers
Discovery of (3-endo)-3-(2-cyano-2,2-diphenylethyl)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane bromide as an efficacious inhaled muscarinic acetylcholine receptor antagonist for the treatment of COPD
Wan, Zehong,Laine, Dramane I.,Yan, Hongxing,Zhu, Chongjie,Widdowson, Katherine L.,Buckley, Peter T.,Burman, Miriam,Foley, James J.,Sarau, Henry M.,Schmidt, Dulcie B.,Webb, Edward F.,Belmonte, Kristen E.,Palovich, Michael
scheme or table, p. 4560 - 4562 (2010/04/24)
Design and syntheses of a novel series of muscarinic antagonists are reported. These efforts have culminated in the discovery of (3-endo)-3-(2-cyano-2,2-diphenylethyl)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane bromide (4a) as a potent and pan-active musca
