56880-11-6

Upstream product

• 94407-38-2 (+/-)-cyano-tropane-3endo-yl-acetic acid ethyl ester 
• 688-49-3 ethyl (diethoxyphosphino)acetate 
• 532-24-1 tropinone 
• 64-17-5 ethanol 
• 56880-12-7 endo-8-methyl-8-azabicyclo<3.2.1>octane-3-acetic acid 
• 2858-77-7 ethyl (8-methyl-8-azabicyclo<3.2.1>oct-3-ylidene)acetate 

Downstream Products

• 106655-98-5 3endo-(2-hydroxy-2,2-diphenyl-ethyl)-8,8-dimethyl-nortropanium; bromide 
• 850607-53-3 3-[(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,2-diphenylpropanenitrile 
• 101058-02-0 3endo-(2,2-diphenyl-vinyl)-tropane 
• 1428587-19-2 8-(2-(benzyloxy)ethyl)-3-(2-cyano-2,2-diphenylethyl)-8-methyl-8-azabicyclo[3.2.1]octan-8-ium bromide 
• 852436-01-2 8-(2-(benzyloxy)ethyl)-3-(2-cyano-2,2-diphenylethyl)-8-methyl-8-azabicyclo[3.2.1]octan-8-ium bromide 
• 1428580-74-8 3-(8-methyl-8-azabicyclo-[3.2.1]octan-3-yl)-2,2-diphenylpropanenitrile hydrochloride 
• 852435-98-4 3-(8-(2-(benzyloxy)ethyl)-8-azabicyclo[3.2.1]octan-3-yl)-2,2-diphenylpropanenitrile 
• 1428580-77-1 3-(8-azabicyclo[3.2.1]octan-3-yl)-2,2-diphenylpropanenitrile hydrochloride 
• 1374137-56-0 8-(2-(benzyloxy)ethyl)-3-(2-cyano-2,2-diphenylethyl)-8-methyl-8-azabicyclo[3.2.1]octan-8-ium iodide 
• 119016-27-2 (+/-)-3endo-(4-cyclohexyl-2-hydroxy-2-phenyl-butyl)-8,8-dimethyl-nortropanium; bromide 
• 106713-93-3 (+/-)-3endo-(2-cyclohexyl-2-hydroxy-2-phenyl-ethyl)-8,8-dimethyl-nortropanium; bromide 
• 108042-35-9 3endo-(2,2-diphenyl-vinyl)-8,8-dimethyl-nortropanium; bromide 
• 103034-31-7 (+/-)-4-cyclohexyl-2-phenyl-1-tropane-3endo-yl-butan-2-ol 
• 103034-27-1 (+/-)-3endo-(4-cyclohexyl-2-phenyl-butyl)-tropane 

Relevant academic research and scientific papers

The synthesis, conformation and antimuscarinic properties of ketone analogues of tropane esters

A synthesis of the ketone analogues of three naturally occurring tropane esters has been developed and one of the ketones has been evaluated for its efficacy as a muscarinic acetylcholine receptor (mAChR) antagonist in guinea-pig ileum. The ketone analogu

Design, synthesis, and structure - Activity relationship of tropane muscarinic acetylcholine receptor antagonists

Novel tropane derivatives were characterized as muscarinic acetylcholine receptor antagonists (mAChRs). Through optimization of the structure - activity relationship around the tropane scaffold, the quaternary ammonium salt 34 was identified as a very pot

M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS

Muscarinic Acetylcholine receptor antagonists and methods of using them are provided.

M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS

Muscarinic Acetylcholine receptor antagonists and methods of using them are provided.

Synthesis and biological evaluation of tropane-like 1-{2-[bis(4-fluorophenyl)methoxy]ethyl})-4-(3-phenylpropyl)piperazine (GBR 12909) analogues

We have prepared azabicyclo[3.2.1] derivatives (C-3-substituted tropanes) that bind with high affinity to the dopamine transporter and inhibit dopamine reuptake. Within the series, 3-{(2-[bis-(4-fluorophenyl)methoxy] ethylidene}-8-methyl-8-azabicyclo[3.2.

New 5-HT3 (serotonin-3) receptor antagonists. IV. Synthesis and structure-activity relationships of azabicycloalkaneacetamide derivatives.

The synthesis and structure-activity relationships of a series of new azabicycloalkanes as 5-HT3 (serotonin-3) receptor antagonists are described. Our study on the azabicycloalkaneacetamide derivatives showed that 2,3-dihydroindole as the aromatic ring mo