106658-99-5

Upstream product

• 92500-59-9 α-(2,2-diethoxyethyl)benzyl cyanide 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 
• 140-29-4 phenylacetonitrile 

Downstream Products

• 19509-06-9 1-methyl-3-phenylpyrrolidine 
• 88897-80-7 4-Acetylamino-5-chloro-2-methoxy-N-((2S,7R,8aR)-2-phenyl-octahydro-indolizin-7-yl)-benzamide 
• 88897-80-7 4-Acetylamino-5-chloro-2-methoxy-N-((2R,7R,8aR)-2-phenyl-octahydro-indolizin-7-yl)-benzamide 
• 88907-26-0 (2α,7α,8aβ)-4-amino-5-chloro-2-methoxy-N-(octahydro-2-phenylindolizin-7-yl)benzamide 
• 88907-26-0 (2β,7α,8aβ)-4-amino-5-chloro-2-methoxy-N-(octahydro-2-phenylindolizin-7-yl)benzamide 
• 88897-72-7 (2R,8aS)-2-Phenyl-hexahydro-indolizin-7-one oxime 
• 88897-72-7 (2S,8aS)-2-Phenyl-hexahydro-indolizin-7-one oxime 
• 88897-71-6 (2R,7S,8aS)-2-Phenyl-octahydro-indolizin-7-ylamine 
• 88897-71-6 (2R,7R,8aR)-2-Phenyl-octahydro-indolizin-7-ylamine 
• 115114-04-0 (2α,5α,7α,8aβ)-4-amino-5-chloro-2-methoxy-N-(octahydro-5-methyl-2-phenylindolizin-7-yl)benzamide 
• 115114-08-4 (2R,5R,7S,8aS)-5-Methyl-2-phenyl-octahydro-indolizin-7-ylamine 
• 88897-67-0 (2R,8aR)-2-Phenyl-hexahydro-indolizin-7-one 
• 88897-67-0 (2R,8aS)-2-Phenyl-hexahydro-indolizin-7-one 

Relevant academic research and scientific papers

Substituted Benzamides with Conformationally Restricted Side Chains. 2. Indolizine Derivatives as Central Dopamine Receptor Antagonists

The substituted benzamides metoclopramide (1) and clebopride (3) are stimulants of gastric molitity.They are also central dopamine receptor antagonists with 3 being the more potent.This is presumed to be due to an additional interaction of its N-benzyl gr

Synthesis of Quinolizidines and Indolizidines via an Intramolecular Mannich Reaction

Acid treatment of the addition products (13) of an aminopentanal or aminobutanal diethyl acetal and an α,β-unsaturated ketone gave the quinolizidin-2-ones (11), (12), (20), (36), and (37) and the indolizidin-7-ones (9), (10), (16)-(19), (34), and (35) res