106664-04-4

Basic information

• Product Name: 6,7-dimethoxy-2-phenylbenzo[d][1,2]selenazol-3(2H)-one
• Synonyms: 6,7-dimethoxy-2-phenylbenzo[d][1,2]selenazol-3(2H)-one
• CAS NO: 106664-04-4
• Molecular Weight: 334.233
• Mol File: 106664-04-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6,7-dimethoxy-2-phenylbenzo[d][1,2]selenazol-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-dimethoxy-2-phenylbenzo[d][1,2]selenazol-3(2H)-one(106664-04-4)
• EPA Substance Registry System: 6,7-dimethoxy-2-phenylbenzo[d][1,2]selenazol-3(2H)-one(106664-04-4)

Safety Data

• Hazardous Substances Data: 106664-04-4(Hazardous Substances Data)

Upstream product

• 106506-36-9 2-chloro-3,4-dimethoxy-N-phenylbenzamide 
• 106663-89-2 2,2-Diselenobis-[N-phenyl-(3,4-dimethoxy-benzamide)] 
• 1522-67-4 N-phenyl-3,4-dimethoxybenzamide 

Relevant articles and documents

Copper catalyzed/mediated synthetic methodology for ebselen and related isoselenazolones

Scope of the copper catalyzed/mediated selenium-nitrogen coupling reaction has been studied for the synthesis of isoselenazolones. It is noticed that the 2-chloro, 2-bromo-, and 2-iodo-aryl amides substrates can be exploited in the selenium-nitrogen coupling reaction by employing 25-100 mol % of CuI/1,10-phenanthroline (L) and potassium carbonate as a base in DMF. Furthermore, electron rich 2-chloro-arylamides also underwent selenium-nitrogen coupling reaction to give biologically important selenium-nitrogen heterocycles. Also, copper-catalyzed selenium-nitrogen coupling reaction has been meticulously applied for the synthesis of diaryl diselenides having methoxy, amine, and amide functionality from respective aryl iodides in the presence of stoichiometric amount of succinimide as an external Se-N coupling partner.