1522-67-4

Usage

Uses

Used in Pharmaceutical Industry:
3,4-DIMETHOXYBENZANILIDE is used as a synthetic intermediate for the production of various pharmaceuticals, leveraging its structural features to facilitate the creation of new drug molecules with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 3,4-DIMETHOXYBENZANILIDE is utilized as a precursor in the synthesis of compounds with pesticidal properties, contributing to the development of effective solutions for crop protection and management.
Used in Organic Synthesis:
3,4-DIMETHOXYBENZANILIDE is employed as a versatile building block in organic synthesis, enabling the construction of a wide range of chemical entities with diverse applications across various industries.
Used in Pharmacological Research:
3,4-DIMETHOXYBENZANILIDE is studied for its potential pharmacological properties, such as antiviral and analgesic effects. Its exact mechanisms of action and potential applications are still under investigation, indicating a promising avenue for future research and development in the field of medicine.

Upstream product

• 62-53-3 aniline 
• 3535-37-3 3,4-dimethoxybenzoic acid chloride 
• 27895-67-6 N-(3,4-dimethoxybenzylidene)aniline 
• 93-07-2 Veratric acid 
• 91-16-7 1,2-dimethoxybenzene 
• 103-72-0 phenyl isothiocyanate 
• 103-71-9 phenyl isocyanate 
• 122775-35-3 3,4-Dimethoxyphenylboronic acid 
• 701-73-5 methyl N-phenyldithiocarbamate 
• 5378-52-9 phenyl-1H-tetrazole 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 4930-03-4 phenyl N-phenylcarbamate 
• 4038-14-6 3,4-dimethoxybenzophenone 
• 7553-56-2 iodine 

Downstream Products

• 115802-61-4 N-phenyl-3,4-dimethoxy-2-(4'-methoxybenzyl)benzamide 
• 117671-67-7 4,5-dimethoxy-3-(4'-methoxyphenyl)phthalide 
• 92552-99-3 2-(3,4-dimethoxyphenyl)-1,3-benzoxazole 
• 1103414-83-0 N-(isoquinolin-1-yl)-3,4-dimethoxy-N-phenylbenzamide 
• 106664-04-4 6,7-dimethoxy-2-phenylbenzo[d][1,2]selenazol-3(2H)-one 
• 115831-71-5 3,4-dihydro-3-hydroxy-5,6-dimethoxy-4-(4'-methoxyphenyl)-2-methylisoquinolin-1(2H)-one 
• 115802-60-3 5,6-dimethoxy-4-(4'-methoxyphenyl)-2-methylisoquinolin-1(2H)-one 
• 115802-59-0 N-methyl-3,4-dimethoxy-2-(4'-methoxybenzyl)benzamide 
• 115888-85-2 (+/-)-latifine dimethyl ether 
• 115802-58-9 3,4-dimethoxy-2-(4'-methoxybenzyl)benzoic acid 
• 4741-58-6 4,5-dimethoxyisobenzofuran-1(3H)-one 
• 1620644-87-2 N-[2-(3-acetyl-1-benzyl-pyridin-1-ium-4-yl)ethyl]-3,4-dimethoxy-N-phenyl-benzamide 2,3-dichloro-5,6-dicyano-4-oxo-cyclohex-1,5-dien-1-olate 
• 1620644-83-8 N-[2-(3-acetyl-1-benzyl-4H-pyridin-4-yl)ethyl]-3,4-dimethoxy-N-phenyl-benzamide 
• 1620646-07-2 3,4-dimethoxy-N-[(E)-5-oxopent-3-enyl]-N-phenyl-benzamide 

Relevant academic research and scientific papers

Studies on enamides. Part-5: A novel pathway for photochemical reaction of N-1-cyclohexenyl-N-phenylarylamides

The oxidative photolysis of N-1-cyclohexenyl-N-phenylarylamides has culminated in the photochemical synthesis of anilides by a novel reaction pathway.

Rhodium-Catalyzed Synthesis of Amides from Functionalized Blocked Isocyanates

Isocyanates are useful building blocks for the synthesis of amides, although their widespread use has been limited by their high reactivity, which often results in poor functional group tolerance and a propensity to oligomerize. Herein, a rhodium-catalyzed synthesis of amides is described coupling boroxines with blocked (masked) isocyanates. The success of the reaction hinges on the ability to form both the isocyanate and the organorhodium intermediates in situ. Relying on masked isocyanate precursors and on the high reactivity of the organorhodium intermediate results in broad functional group tolerance, including protic nucleophilic groups such as amines, anilines, and alcohols.

Synthesis of amides from acid chlorides and amines in the bio-based solvent Cyrene

Cyrene as a bio-alternative dipolar aprotic solvent: a waste minimizing and molar efficient protocol for the synthesis of amides from acid chlorides and primary amines in the bio-available solvent Cyrene is disclosed. This protocol removed the use of toxic solvents, such as dimethylformamide and dichloromethane. A simple aqueous work-up procedure for the removal of the high boiling solvent Cyrene resulted in up to a 55-fold increase in molar efficiency (Mol E.%) versus standard operating procedures. In order to rapidly compare the molar efficiency of this process against other methodologies an Excel based Mol. E% calculator was developed that automates many of the calculations. An investigation into the hydration of Cyrene found that it readily hydrates to form a geminal diol in the presence of water and that this process is exothermic.

A metal-free and a solvent-free synthesis of thio-amides and amides: An efficient Friedel-Crafts arylation of isothiocyanates and isocyanates

A rapid, metal-free and solvent-free (very low loading of solvent in few cases) reaction conditions for synthesizing thioamides and amides using a Bronsted super acid such as triflic acid has been developed. This method shows a broad substrate scope with

Synthesis of amides through an oxidative amidation of tetrazoles with aldehydes under transition-metal-free conditions

A simple, inexpensive and efficient one-pot synthesis of amides was achieved in good yields via the direct oxidative amidation of tetrazoles with aldehydes under transition-metal-free conditions.

Dithiocarbamate and DBU-promoted amide bond formation under microwave condition

Dithiocarbamate and DBU-promoted amide bond formation under microwave condition has been reported. The versatility of this synthetic protocol has been demonstrated with various carboxylic acids and different dithiocarbamates. The products thus obtained ha

Palladium-catalyzed addition of arylboronic acids to isocyanates

The addition of arylboronic acids to isocyanates catalyzed by palladium acetate in the presence of triphenylphosphine as the ligand is described.

Hansch analysis of veratric acid derivatives as antimicrobial agents

The synthesis, characterization and antimicrobial evaluation of a new series of veratric acid derivatives are presented. Preliminary in vitro antimicrobial activity of the title compounds was assessed against a panel of microorganisms including Gram-positive and Gram-negative bacteria and fungi. Some of the veratric acid derivatives exhibited significant in vitro antimicrobial activity. QSAR investigation applied to find a correlation between different physicochemical parameters of the veratric acid derivatives and their antimicrobial activity indicated the importance of topological parameters in describing the antimicrobial activity.

An Efficient Synthesis of (+/-)-Latifine Dimethyl Ether

4,5-Dimethoxy-3-(4'-methoxyphenyl)phthalide (2) was hydrogenolysed to give 3,4-dimethoxy-2-(4'-methoxybenzyl)benzoic acid (3).The N-methylamide of (3) was lithiated and treated with dimethylformamide to furnish 3,4-dihydro-3-hydroxy-5,6-dimethoxy-4-(4'-me

Reaction of Sulphuryl Chloride with Some Schiff Bases

The reaction of sulphuryl chloride with schiff bases has been studied.In each case, pure crystalline products have been isolated, and their structures elucidated on the basis of IR, PMR and mass spectral data.A plausible mechanism is advanced for the formation of observed products.