106670-23-9Relevant academic research and scientific papers
IMIDAZOLYL ALKYL GUANIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS
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, (2008/06/13)
New imidazolylalkyl-guanidine derivatives are described, which by virtue of their agonistic action on histamine-H 2 receptors and in part also due to their additional H 1-antagonistic receptor activity can be used in the treatment of cardiac diseases, certain forms of hypertension and diseases of arterial occlusion.These imidazolylalkyl-guanidine derivatives correspond to the general formula I: STR1
Synthesis and pharmacological activity of arylmethylthioethylguanidines
Buschauer
, p. 1008 - 1012 (2007/10/02)
Impromidine analogues guanidines have been prepared characterized by H2-unspecific arylmethyl groups instead of the 5-methylimidazole residue. The most potent substances proved to be about 20 times more active than histamine at the isolated spo
