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38336-04-8

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38336-04-8 Usage

Synthesis Reference(s)

Tetrahedron Letters, 36, p. 3465, 1995 DOI: 10.1016/0040-4039(95)00527-J

Check Digit Verification of cas no

The CAS Registry Mumber 38336-04-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,3,3 and 6 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 38336-04:
(7*3)+(6*8)+(5*3)+(4*3)+(3*6)+(2*0)+(1*4)=118
118 % 10 = 8
So 38336-04-8 is a valid CAS Registry Number.

38336-04-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(Benzyloxy)-Ethylamine

1.2 Other means of identification

Product number -
Other names 2-phenylmethoxyethanamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:38336-04-8 SDS

38336-04-8Relevant articles and documents

A N - benzyl ethanolamine preparation method

-

Paragraph 0023-0028, (2019/06/05)

A N - benzyl ethanolamine preparation method, including the use of ethanolamine and benzyl chloride as the raw material, to solid phase alkali as the reaction of the acid and alkaline catalyst, in the 40 - 120 °C under stirring to carry out the condensation reaction, the reaction after the stop of the take methylethanone, the filtrate to carry out rectification under vacuum, collecting the fraction, product N - benzyl ethanolamine. This invention adopts the solid phase alkali to [...] and catalytic, through the solid-liquid two-phase are a temperature and reaction to improve the main the selectivity of the reaction, in order to improve the synthetic yield; compared with original craft, saves the sodium hydroxide solution used for washing with ethyl acetate extraction of complex process a plurality of times; at the same time as solid phase alkali acid and alkaline catalyst with hydrogen chloride the reaction generates sodium chloride, convenient recycling, realizes the zero discharge of waste water; improves the ethanolamine utilization rate of the raw material; the invention is not only simple and convenient operation, production process economic and environmental protection, few by-products, and the synthetic yield has been raised by 25 - 30%, preparation and reducing the cost to 30 - 35%.

Design, synthesis and antimycobacterial activity of novel imidazo[1,2-a]pyridine-3-carboxamide derivatives

Lv, Kai,Li, Linhu,Wang, Bo,Liu, Mingliang,Wang, Bin,Shen, Weiyi,Guo, Huiyuan,Lu, Yu

, p. 117 - 125 (2017/06/05)

We report herein the design and synthesis of “novel imidazo [1,2-a]pyridine-3-carboxamides (IPAs)” bearing a variety of different linkers, based on the structure of IMB-1402 discovered in our lab. Results reveal that 2,6-dimethyl-N-[2-(phenylamino)ethyl] IPAs with an electron-donating group on the benzene ring as a potent scaffold. Compounds 26g and 26h have considerable activity (MIC: 0.041–2.64 μM) against drug-sensitive/resistant MTB strains, and they have acceptable safety indices against MTB H37Rv with the SI values of 4395 and 1405, respectively. Moreover, N-[2-(piperazin-1-yl)ethyl] moiety was also identified as a potentially alternative linker (compound 31), opening a new direction for further SAR studies.

An Iodine-Catalyzed Hofmann-L?ffler Reaction

Martínez, Claudio,Mu?iz, Kilian

supporting information, p. 8287 - 8291 (2015/07/07)

Iodine reagents have been identified as economically and ecologically benign alternatives to transition metals, although their application as molecular catalysts in challenging C-H oxidation reactions has remained elusive. An attractive iodine oxidation catalysis is now shown to promote the convenient conversion of carbon-hydrogen bonds into carbon-nitrogen bonds with unprecedented complete selectivity. The reaction proceeds by two interlocked catalytic cycles comprising a radical chain reaction, which is initiated by visible light as energy source. This unorthodox synthetic strategy for the direct oxidative amination of alkyl groups has no biosynthetic precedence and provides an efficient and straightforward access to a general class of saturated nitrogenated heterocycles.

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