1067324-71-3Relevant academic research and scientific papers
Highly functionalised (γ-azido/γ-fluoro-β-iodo/)vinyl derivatives from phosphorus based allenes or allenoates: I?O halogen bonding interactions
Anitha, Mandala,Kumara Swamy
, p. 5736 - 5748 (2019)
Multifunctional γ-azido/γ-fluoro-β-iodo-vinyl phosphine oxides/phosphonates/esters/sulfone were synthesised by iodination followed by azidation/fluorination of phosphorus-based allenes or allenoates (allenyl esters) or a sulphur based allene. Surprisingly, the reaction of (γ,β)-diiodo-vinyl-phosphonate with TBAF [n-Bu4NF] led to the corresponding allenylphosphonate; in contrast, the use of CsF in a similar reaction led to novel γ-diiodo-allenylphosphonate along with the corresponding non-halogenated allenylphosphonate. The combination AgF2/CuBr could be used to obtain the γ-fluoro-β-iodo-vinyl phosphine oxides and related phosphorus-free γ-fluoro-β-iodo-vinyl esters. In many cases, I?O halogen to oxygen non-covalent bonding interactions ('halogen bonding') involving the phosphoryl (PO) oxygen, as evidenced by single crystal X-ray crystallography, are also observed.
Neighboring group participation of phosphine oxide functionality in the highly regio- and stereoselective iodohydroxylation of 1,2-allenylic diphenyl phosphine oxides
Guo, Hao,Qian, Rong,Guo, Yinlong,Ma, Shengming
, p. 7934 - 7938 (2008/12/22)
(Chemical Equation Presented) Two sets of reaction conditions were established to enable the highly regio- and stereoselective iodohydroxylation of 1,2-allenylic diphenyl phosphine oxides, yielding (E)-2-iodo-3-hydroxy-1- alkenyl diphenyl phosphine oxides
