17620-99-4Relevant academic research and scientific papers
The organocatalytic enantiodivergent fluorination of β-ketodiaryl-phosphine oxides for the construction of carbon-fluorine quaternary stereocenters
Xie, Shaolei,He, Zhi-Juan,Zhang, Ling-Hui,Huang, Bo-Lun,Chen, Xiao-Wei,Zhan, Zong-Song,Zhang, Fu-Min
supporting information, p. 2069 - 2072 (2021/03/01)
Commercially available cinchona alkaloids that can catalyze the enantiodivergent fluorination of β-ketodiarylphosphine oxides were developed to construct carbon-fluorine quaternary stereocenters. This protocol features a wide scope of substrates and excellent enantioselectivities, and it is scalable.
Direct Access to Allenylphosphine Oxides via a Metal Free Coupling of Propargylic Substrates with P(O)H Compounds
Yang, Chun-Hua,Fan, Huihui,Li, Huimin,Hou, Shenyin,Sun, Xiangkun,Luo, Donghao,Zhang, Yinchao,Yang, Zhantao,Chang, Junbiao
, p. 9438 - 9441 (2019/11/20)
A direct and convenient approach for the coupling of propargylic substrates with diphenylphosphine oxide in the presence of Tf2O and 2,6-lutidine has been developed. The method provides a general approach for the construction of attractive allenylphosphoryl skeletons with high atom and step economy under metal free conditions.
Ambient temperature hydrophosphination of internal, unactivated alkynes and allenyl phosphineoxides with phosphine borane complexes
Busacca, Carl A.,Farber, Elisa,Deyoung, Jay,Campbell, Scot,Gonnella, Nina C.,Grinberg, Nelu,Haddad, Nizar,Lee, Heewon,Ma, Shengli,Reeves, Diana,Shen, Sherry,Senanayake, Chris H.
supporting information; experimental part, p. 5594 - 5597 (2010/03/05)
[Chemical Equation Presented] Phosphine boranes have been found to hydrophosphinate Internal, unactivated alkynes at room temperature under basic conditions without the need for catalysts or radical initiators. The use of air-sensitive secondary phosphine
Neighboring group participation of phosphine oxide functionality in the highly regio- and stereoselective iodohydroxylation of 1,2-allenylic diphenyl phosphine oxides
Guo, Hao,Qian, Rong,Guo, Yinlong,Ma, Shengming
, p. 7934 - 7938 (2008/12/22)
(Chemical Equation Presented) Two sets of reaction conditions were established to enable the highly regio- and stereoselective iodohydroxylation of 1,2-allenylic diphenyl phosphine oxides, yielding (E)-2-iodo-3-hydroxy-1- alkenyl diphenyl phosphine oxides
Rhodium-catalyzed asymmetric hydroarylation of diphenylphosphinylallenes with arylboronic acids
Nishimura, Takahiro,Hirabayashi, Sho,Yasuhara, Yuichi,Hayashi, Tamio
, p. 2556 - 2557 (2007/10/03)
Rhodium-catalyzed asymmetric hydroarylation of diphenylphosphinylallenes with arylboronic acids proceeded in high yields with high regio- and enantioselectivity to give chiral allylphosphine oxides of up to 98% ee. The structural determination of the key
Double phosphinylation of propargylic alcohols: A novel synthetic route to 1,2-bis(diphenylphosphino)ethane derivatives
Milton, Marilyn Daisy,Onodera, Gen,Nishibayashi, Yoshiaki,Uemura, Sakae
, p. 3993 - 3995 (2007/10/03)
(Chemical Equation Presented) Double phosphinylation of propargylic alcohols with diphenylphosphine oxide in the presence of a thiolate-bridged diruthenium complex as catalyst gives the corresponding 2,3- bis(diphenylphosphinyl)-1-propenes in high yields
