106748-27-0

Upstream product

• 106748-24-7 methyl 3-carbamoylbenzoate 
• 3441-03-0 3-(methoxycarbonyl)benzoyl chloride 
• 1877-71-0 benzene 1,3-dicarboxylic acid monomethyl ester 
• 1459-93-4 dimethyl Isophthalate 
• 13531-48-1 methyl 3-cyanobenzoate 

Downstream Products

• 247088-30-8 methyl 3-[(4-phenyl)thiazol-2-yl]benzoate 
• 473538-10-2 3-(4-hydroxymethyl-thiazol-2-yl)-benzoic acid methyl ester 
• 247088-32-0 methyl 3-{3-[(4-phenyl)thiazol-2-yl]benzamido}propyl sulfide 
• 1089729-76-9 (R)-2-[2-(3-methoxycarbonyl-phenyl)-thiazol-4-yl]-piperidine-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Cyclic derivatives as modulators of chemokine receptor activity

The present application describes modulators of MCP-1 of formula (I): or pharmaceutically acceptable salt forms thereof, useful for the treatment of rheumatoid arthritis, multiple sclerosis, atherosclerosis and asthma.

Substituted cycloalkylamine derivatives as modulators of chemokine receptor activity

The present application describes modulators of MCP-1 of formula (I): or pharmaceutically acceptable salt forms thereof, useful for the prevention of asthma, multiple sclerosis, artherosclerosis, and rheumatoid arthritis.

Synthesis and properties of some novel anti-calmodulin drugs

The preparation and properties of some novel inhibitors of calmodulin function are described. The compounds are cationic derivatives of phenyl-substituted thiazoles which inhibit the calmodulin stimulation of cyclic-AMP phosphodiesterase and are active against animal tumor cells in culture. These derivatives form the basis for the preparation of new, more potent inhibitors of calmodulin function which could take advantage of the reported elevated levels of calcium-bound calmodulin in tumor cells and show preferential anti-tumor activity. Copyright (C) 1999 Elsevier Science Ltd.