106748-24-7

Basic information

• Product Name: METHYL3-(AMINOCARBONYL)BENZOATE
• Synonyms: methyl 3-carbamoylbenzoate;Benzoic acid, 3-(aMinocarbonyl)-, Methyl ester;3-(Methoxycarbonyl)benzamide, Methyl isophthalamate
• CAS NO: 106748-24-7
• Molecular Formula: C₉H₉NO₃
• Molecular Weight: 179.18
• Mol File: 106748-24-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 147～150℃
• Boiling Point: 318.5 °C at 760 mmHg
• Flash Point: 167.4 °C
• Appearance: /
• Density: 1.226 g/cm³
• Vapor Pressure: 0.00036mmHg at 25°C
• Refractive Index: 1.556
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 15.41±0.50(Predicted)
• CAS DataBase Reference: METHYL3-(AMINOCARBONYL)BENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL3-(AMINOCARBONYL)BENZOATE(106748-24-7)
• EPA Substance Registry System: METHYL3-(AMINOCARBONYL)BENZOATE(106748-24-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 106748-24-7(Hazardous Substances Data)

Usage

General Description

Methyl3-(aminocarbonyl)benzoate, also known as C10H11NO4 in terms of its molecular formula, is one of the numerous types of benzoate ester. It falls under the category of organic compounds, which means it is carbon-based, and it contains one carboxylic acid ester functional group. This chemical compound is relatively less common and specific details about its characteristics or potential uses are limited. However, benzoate esters in general are often used in industries such as food and beverage, pharmaceutical, and cosmetic for their antimicrobial properties or as flavoring agents. Safety and handling information should be researched and followed as it may pose potential health risks.-

InChI:InChI=1/C9H9NO3/c1-13-9(12)7-4-2-3-6(5-7)8(10)11/h2-5H,1H3,(H2,10,11)

Upstream product

• 3441-03-0 3-(methoxycarbonyl)benzoyl chloride 
• 1459-93-4 dimethyl Isophthalate 
• 1877-71-0 benzene 1,3-dicarboxylic acid monomethyl ester 
• 13531-48-1 methyl 3-cyanobenzoate 
• 925159-45-1 C₁₆H₁₅NO₃ 
• 77-78-1 dimethyl sulfate 
• 201230-82-2 carbon monoxide 
• 618-91-7 methyl 3-iodo-benzoate 

Downstream Products

• 288082-69-9 C₃₁H₃₅N₅O₆ 
• 247088-32-0 methyl 3-{3-[(4-phenyl)thiazol-2-yl]benzamido}propyl sulfide 
• 247088-30-8 methyl 3-[(4-phenyl)thiazol-2-yl]benzoate 
• 106748-27-0 3-thiocarbamoyl-benzoic acid methyl ester 
• 4481-28-1 3-carboxybenzamide 
• 13531-48-1 methyl 3-cyanobenzoate 

Relevant articles and documents

A palladium-catalyzed carbonylative route to primary amides

The palladium-catalyzed reaction of aryl and vinyl iodides and triflates with carbon monoxide in the presence of hexamethyldisilazane followed by hydrolytic work-up affords aromatic and α,β-unsaturated primary amides in good to high yields under relatively mild conditions.

Selective aerobic hydrolysis of nitriles to amides using cobalt(II)/zinc

A novel protocol has been developed for the aerobic hydrolysis of nitriles to amides using cobalt(II)/zinc without using any strong acids and bases under solvent-free conditions. The reaction showed good performance for benzonitriles with sensitive groups such as ester and carboxylic acid.

Synthesis and properties of some novel anti-calmodulin drugs

The preparation and properties of some novel inhibitors of calmodulin function are described. The compounds are cationic derivatives of phenyl-substituted thiazoles which inhibit the calmodulin stimulation of cyclic-AMP phosphodiesterase and are active against animal tumor cells in culture. These derivatives form the basis for the preparation of new, more potent inhibitors of calmodulin function which could take advantage of the reported elevated levels of calcium-bound calmodulin in tumor cells and show preferential anti-tumor activity. Copyright (C) 1999 Elsevier Science Ltd.